Transient Co-Expression of Bioactive Murine Interferon-Gamma and HBsAg in Tobacco and Lettuce Leaves
Sara Mohammadzadeh,
Mahshid Amiri,
Parastoo Ehsani
Abstract:Background: The synchronous expression of antigen and adjuvant proteins in plant hosts presents an intriguing potential for vaccine production and the enhancement of appropriate immune responses. In this study, we examined the expression of bioactive murine interferon-gamma (mIFN-γ) along with HBsAg in tobacco and lettuce leaves aimed to further perform the analysis of immune responses in the mouse model.
Methods: Monocistronic and bicistronic cassettes, carrying genes encoding mIFN-γ and HBsAg in variou… Show more
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