Transient asymptomatic S-T segment depression during daily activity

Schang, Steven J.; Pepine, Carl J.

doi:10.1016/s0002-9149(77)80095-7

Cited by 569 publications

(38 citation statements)

References 12 publications

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“…In conclusion, our results confirm previous preliminary reports (Cocco et al, 1979;Germand et al, 1980;Schang and Pepine, 1977;Sellier et al, 1978;Stern et al, 1975): The usual criterion of chest pain during daily activity may underestimate the actual frequency of ischemic events in some patients with CAD and stable angina pectoris. In selected patients, good DCG monitoring is useful in the detection of TMI and in the evaluation of the antianginal therapy.…”

Section: Discussionsupporting

confidence: 92%

“…Furthermore, it has been shown that only a minority of these ischemic episodes are accompanied by chest pain (Biagini et al, 1982;Cocco et al, 1979;Germanb el al., 1980;Johnson rt al., 1982;Maseri ef al., 1978;Previtali el al., 1980;Schang and Pepine, 1977). It is therefore possible that the usual criterion of chest pain and effort-induced ECG changes may underestimate the actual frequency of TMI.…”

Section: Introductionmentioning

confidence: 99%

“…Most studies, however, have been in patients with unstable (Biagini et al, 1982;Haiat et al, 1976;Johnson er al., 1982;Previtali et a/., 1980;Sellier et al, 1978;Selwyn et al, 1978) or variant angina pectoris (MacAlpin, 1980a,b;Maseri et al, 1978;Rozanski er al., 1978). Only a few have been performed in patients with stable angina pectoris (Cocco et al, 1979;Schang and Pepine, 1977; Stern er a f . , 1975) and these have been relatively simple in design.…”

Section: Introductionmentioning

confidence: 99%

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Asymptomatic myocardial ischemia in patients with stable and typical angina pectoris

Cocco

Strozzi

Leishman

et al. 1982

Clinical Cardiology

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Summary:The existence of transient niyocardial ischemia (TMI) and the value of the serial dynamic electrocardiogram (DCG) in patients with variant or unstable angina pectoris are known. However, less information is available on the frequency and characteristics of TMI in patients with stable angina pectoris. For this study, we selected 40 patients with stable and typical angina pectoris. The presence of coronary artery disease and the ejection fraction were evaluated by means of angiocardiography. The DCG monitoring was performed with bichannel portable recorders for three 24-h periods at 7-day intervals. The patients were on optimal doses of beta blockers and isosorbidilate throughout the study.We detected 788 episodes of TMI in 22 of the 40 patients. The ejection fraction was poorer in the 22 patients with ST-Tchanges than in the 18 without such changes. The repolarization changes were: ( I ) ST elevation (55 symptomatic and 87 asymptomatic episodes, (2) ST depression ( 1 38 symptomatic and 236 asymptomatic episodes. and (3) T-wave changes (83 symptomatic and 164 asymptomatic episodes). All 22 patients with TMI prcsented a combination of the above changes. It appears, therefore, that ST-T changes are more frequent in patients with stable angina pectoris than was hitherto suspected. The DCG is valuable in assessing these

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Section: Discussionsupporting

confidence: 92%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Asymptomatic myocardial ischemia in patients with stable and typical angina pectoris

Cocco

Strozzi

Leishman

et al. 1982

Clinical Cardiology

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“…28 Twenty patients with angiographically confirmed coronary artery disease and positive exercise tests were each monitored for several 10-hour periods over the course of 16 months. In the total of 2286 hours of technically adequate recordings, 411 episodes of transient ST-segment abnormalities were documented, of which 308 (75%) were asymptomatic.…”

Section: Patients With Anginamentioning

confidence: 99%

“…In the total of 2286 hours of technically adequate recordings, 411 episodes of transient ST-segment abnormalities were documented, of which 308 (75%) were asymptomatic. Schang and Pepine 28 indirectly "proved" that the silent ST-segment episodes were truly ischemic by markedly reducing their occurrence with the use of prophylactic nitrate preparations.…”

Section: Patients With Anginamentioning

confidence: 99%