Transient acute myositis in childhood.

McKinlay, Ian; Mitchell, Ian

doi:10.1136/adc.51.2.135

Cited by 35 publications

(15 citation statements)

References 10 publications

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“…No immunoglobulin or complement deposits have been reported in muscle biopsy specimens from patients with BACM, but influenza B virus has been isolated from the leg muscle of an infected patient who also had a positive nasopharyngeal culture, and influenza A has been isolated from the thigh of a man who appeared to have had an atypical influenza A infection (5,6). BACM has less frequently been documented to occur after other viral infections such as parainfluenza and adenovirus infection (5,10,11). Key elements in the diagnosis of BACM are a preceding viral URI with symptoms typical of an uncomplicated viral influenza infection such as fever, malaise, cough, sore throat, headache, and rhinitis followed by the acute onset of typical clinical findings of myositis predominantly affecting the gastrocnemius and soleus muscles with an elevated CK level.…”

Section: Discussionmentioning

confidence: 94%

A Child with Benign Acute Childhood Myositis After Influenza

Heiner

Ball

2010

The Journal of Emergency Medicine

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Section: Discussionmentioning

confidence: 94%

A Child with Benign Acute Childhood Myositis After Influenza

Heiner

Ball

2010

The Journal of Emergency Medicine

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“…The median age was 9.3 years (range [3][4][5][6][7][8][9][10][11][12][13][14]. In contrast to uncomplicated cases of IAM, which had a male predominance of 2:1 and usually affected the lower extremities, influenza-associated rhabdomyolysis occurred more often in girls (4:1), and pain and tenderness were mostly diffuse.…”

Section: Review Of the Literaturementioning

confidence: 99%

Influenza-Associated Myositis in Children

et al. 2004

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Background: Influenza-associated myositis (IAM) is an infrequent and poorly known complication of influenza virus infection in children. The aim of this study was to describe five cases of IAM and to review the literature on IAM in children. Patients and Methods:We conducted a retrospective analysis of cases of IAM diagnosed at two university children's hospitals in Switzerland during two consecutive influenza seasons. Findings were compared with 39 individual case reports and five publications summarizing an additional 272 cases identified by a medical online library (MEDLINE) search. Results: Overall, 316 cases were analyzed. IAM typically occurred in school-aged children with a 2:1 male predominance. Influenza B and A viruses were identified in 76% and 24% of cases, respectively. The median interval between onset of influenza and onset of IAM was 3 days (range 0-18). The calf muscles were involved alone or together with other muscle groups in 69% and 31% of cases, respectively. Blood creatine phosphokinase (CPK) concentration was invariably elevated. Median duration to clinical recovery was 3 days (range 1-30). Rhabdomyolysis occurred in ten of 316 patients (3%), was more common in girls (80%), more often associated with influenza A (86%), and led to renal failure in eight patients (80%). Conclusion: Clinical and laboratory findings of IAM are highly characteristic and allow a rapid diagnosis during the influenza season.

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“…The affected patients are usually boys aged 4-10 years [2,6,11]. Transient leukocytopenia and/or neutropenia have been described in association with viral myositis [5,7,9] but not as a constant finding. Transient leukocytopenia and/or neutropenia have been described in association with viral myositis [5,7,9] but not as a constant finding.…”

Section: An Epidemic With Influenza B Virus Causing Benign Acute Myosmentioning

confidence: 99%

“…All the patients in our In acute viral myositis according to our knowledge [1,[5][6][7][8][9][10][11] only 24 out of 63 and 4 out of 49 studied patients had leukocytopenia and neutropenia respectively. Electromyography and muscle biopsy were not justified since the process was benign and resolved rapidly.…”

Section: An Epidemic With Influenza B Virus Causing Benign Acute Myosmentioning

confidence: 99%