TransGCN: a semi-supervised graph convolution network–based framework to infer protein translocations in spatio-temporal proteomics
Bing Wang,
Xiangzheng Zhang,
Xudong Han
et al.
Abstract:Protein subcellular localization (PSL) is very important in order to understand its functions, and its movement between subcellular niches within cells plays fundamental roles in biological process regulation. Mass spectrometry–based spatio-temporal proteomics technologies can help provide new insights of protein translocation, but bring the challenge in identifying reliable protein translocation events due to the noise interference and insufficient data mining. We propose a semi-supervised graph convolution n… Show more
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