Transfusion science and practice in developing countries: “…a high frequency of empty shelves….”

Beal, R. W.

doi:10.1046/j.1537-2995.1993.33493242631.x

Cited by 20 publications

(16 citation statements)

References 5 publications

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“…A number of studies have shown that voluntary donors often have a lower prevalence and incidence of infectious transfusion-transmitted diseases than do family/replacement donors and paid donors. 35 Blood centers in sub-Saharan Africa routinely rely on family/replacement or paid donors for a significant percentage of their blood collection needs, often due to shortages in supply of donor blood in the blood banks. 34 Information collected in the Global Database on Blood Safety has repeatedly shown the importance of recruiting voluntary blood donors.…”

Section: Blood Donor Recruitment Selection and Screeningmentioning

confidence: 99%

Transfusion in Economically Restricted and Developing Countries

Schuetz¹,

Clark²

2007

Blood Banking and Transfusion Medicine

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Section: Blood Donor Recruitment Selection and Screeningmentioning

confidence: 99%

Transfusion in Economically Restricted and Developing Countries

Schuetz¹,

Clark²

2007

Blood Banking and Transfusion Medicine

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“…The cost of a single HIV test (US$ 1-3), exceeds the per capita health expenditures of many African countries [2,15,27,38,39]. Other costs are associated with establishing HIV screening, including pur chasing and maintaining laboratory equipment, training personnel and providing appropriate HIV counselling [4,14,24,36,37,40]. In some areas of Africa, blood is trans fused immediately after collection without screening for in fectious agents [10,14,15,18,38,41,42], Transfusion com plications, including transfusion-transmissible infections, are relatively common in Africa.…”

Section: Epidemiology Of Transfusion-associated Hiv Infection In Sub-mentioning

confidence: 99%

“…In Africa, HIV infections are not concentrated in a few transmission categories and occur to a far greater extent in the general population. Another concern is that risk factor exclusion might result in the loss of too many potential donors in a region experiencing chronic shortages of blood [8,14,36,37,42,[60][61][62]. Moreover, many blood donations in Africa are made by patients' relatives or friends [14,15,19].…”

Section: Exclusion Ofdonors At High Riskfor Hiv Infectionmentioning

confidence: 99%

Epidemiology and Prevention of Transfusion-Associated Human Immunodeficiency Virus Transmission in Sub-Saharan Africa

McFarland¹,

Moher²,

Shandera³

et al. 1997

Vox Sanguinis

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Background and objectives: Compared to industrialised nations, countries in sub-Saharan Africa experience a greater amount of transfusion-associated HIV transmission due to high rates of transfusion in some groups of patients, a higher incidence and prevalence of HIV infection in donor populations, a lack of HIV antibody screening in some areas, and a higher residual risk of contamination in blood supplies despite antibody screening. Materials and methods: Epidemiologic review. Results: Epidemiologic evidence supports the effectiveness of three relatively inexpensive strategies to prevent transfusion-associated HIV transmission in sub-Saharan Africa: HIV antibody screening, avoidance of unnecessary use of blood products, and exclusion of donors at high risk of infection. Such prevention strategies have not been universally implemented. Conclusions: International aid to establish and maintain HIV antibody screening programmes, implementation of sound criteria for transfusion, and the search for HIV risk factors to use as donor exclusion criteria must be expanded in the region.

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“…A greater concerted effort is necessary to attract and retain blood donors recruiters. 'Twinning', in which the blood transfusion centre or service in a developed country provides material and other support to its counter part in a DGC or LDC [21], is also being encouraged. [24].…”

Section: Donor Recruitment and Blood Supplymentioning

confidence: 99%

Blood Safety in Developing Countries

Gibbs¹,

Corcoran²

1994

Vox Sanguinis

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This study, based on responses to a questionnaire, was undertaken to define problems in and formulate solutions for improving blood safety in developing countries as part of an effort to monitor the status of blood transfusion services globally. Despite improvements between 1988 and 1992, only 66% of developing countries (DGCs) and 46% of least developed countries (LDCs) screen all blood donations for antibodies to human immunodeficiency viruses; 72% DGCs and 35% LDCs test all donations for hepatitis B surface antigen and 71 and 48%, respectively, for syphilis. The antihuman globulin test is performed routinely in 62% DGCs and 23% LDCs, and inadequate quality assurance in all aspects of preparatory testing is a major weakness in many countries. The blood supply is usually insufficient: none of the LDCs and 9% of the DGCs collect 30 units or more per 1,000 of the population annually. Blood donor systems are totally voluntary and non-remunerated in 15% DGCs and 7% LDCs; 80% DGCs and 93% LDCs rely totally or partially on replacement donors and 25% of both groups on paid donations. The proportion of repeat donors is low (medians: 47% in DGCs, 20% in LDCs), and discard rates for collected blood are often high (up to 33%). Most of the blood collected is transfused as whole blood, and most DGCs and LDCs have inadequate supplies of plasma substitutes for management of acute haemorrhage. The reasons for these problems and suggested solutions are discussed.

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Transfusion science and practice in developing countries: “…a high frequency of empty shelves….”

Cited by 20 publications

References 5 publications

Transfusion in Economically Restricted and Developing Countries

Transfusion in Economically Restricted and Developing Countries

Epidemiology and Prevention of Transfusion-Associated Human Immunodeficiency Virus Transmission in Sub-Saharan Africa

Blood Safety in Developing Countries

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