“…8 The antecedents of patients with TRAVI include patients with hematologic malignancy undergoing induction chemotherapy major surgery, alcohol dependence, kidney failure, and severe liver disease massive transfusion (replacement of total volume for 4days) and cytokine administration (Granulocyte Colony Stimulating Factor (GCSF), it's important to know that many clinical studies have shown that patients with more severe underlying disease are at higher risk of developing lung injury after transfusion. 4,8,9 The clinical presentation is characterized by dyspnea, hypoxemia, arterial hypotension, non-cardiogenic, acute pulmonary edema and fever. 5 During the physical examination the patient showed diffused pulmonary crackles and decreased breath sounds in complementary studies such as chest radiography the patient shows faint, diffuse alveolar infiltrates consistent with pulmonary edema, it's important not to be confused with other conditions including transfusion-associated circulatory overload (TACO), pneumonia, and acute respiratory distress syndrome (ARDS).…”