Transfusion Medicine in Small Animal Practice

Tocci, Lynel J.

doi:10.1016/j.cvsm.2010.02.005

Cited by 66 publications

(128 citation statements)

References 18 publications

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“…mastocytosis, asthma). 10,23,24 In dogs, the triggers of urticaria and/ or anaphylaxis that are supported by original studies or case reports are vaccines, 25 anaesthetics, 26,27 food, 28,29 venoms, [30][31][32] drugs, 1,17 glucocorticoids, 33 transfusions, 34 plants 35 and radiocontrast media. 36 Some rare causes such as heat, exercise, sunlight, dermatographism, estrous, intestinal parasites, allergen-specific immunotherapy and intradermal testing are only anecdotally reported in veterinary textbooks.…”

Section: Introductionmentioning

confidence: 99%

Triggers, risk factors and clinico‐pathological features of urticaria in dogs – a prospective observational study of 24 cases

Rostaher¹,

Hofer‐Inteeworn

Kümmerle‐Fraune

et al. 2017

Advances in Veterinary Dermatology

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Background -Urticaria and anaphylaxis are frequently encountered in veterinary practice, but little is known about the causes and relative frequencies of these reactions.Hypothesis/Objectives -This study was designed to improve current knowledge on the triggers, risk factors and clinico-pathological features of urticaria.Animals -Twenty four dogs with signs of urticaria with or without anaphylaxis.Methods -The study included dogs with cutaneous immediate-type hypersensitivity reactions. The cases were grouped by clinical severity into either an urticaria or an anaphylaxis group. All treatments and diagnostic tests (haematology, biochemical profile, allergy investigation) were recorded. A causality algorithm for urticaria and anaphylaxis (ALUA) was designed to determine the probability of the identified triggers and cofactors. Disease incidence, breed, age and gender predispositions were evaluated statistically.Results -Sixteen of 24 urticaria cases were associated with anaphylaxis whilst 8 of 24 were confined to the skin. The annual hospital incidence was 0.12%. Females seemed to be over-represented (2.4:1) and most of the dog breeds were pure breed (22 of 24), with Rhodesian ridgeback, boxer, beagle, Jack Russell terrier, French bulldog and Vizslas over-represented. In addition to skin lesions, the most frequently and severely affected organ systems were the gastrointestinal and cardiovascular systems. The predominant blood abnormalities were elevated lipase and alanine aminotransferase values. Insects, food and drugs were the most commonly identified triggers.Conclusions -To the best of our knowledge, this is the first study describing the trigger factors and clinicopathological features of dogs with urticaria in veterinary medicine. Insects, food and drugs were the most frequently detected triggers.

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Section: Introductionmentioning

confidence: 99%

Triggers, risk factors and clinico‐pathological features of urticaria in dogs – a prospective observational study of 24 cases

Rostaher¹,

Hofer‐Inteeworn

Kümmerle‐Fraune

et al. 2017

Advances in Veterinary Dermatology

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“…Após uma transfusão incompatível com DEA 1, o receptor de sangue torna-se sensibilizado e uma segunda transfusão incompatí-vel com DEA 1 pode resultar em uma reação transfusional aguda e potencialmente fatal (SPADA et al, 2017;TOCCI, 2010). Historicamente, são apresentados diferentes alelos no DEA 1, sendo DEA 1.1, DEA 1.2 e DEA 1.3.…”

Section: Antígenos Eritrocitários Caninosunclassified

Imunohematologia Veterinária: Antígenos Eritrocitários Caninos

Vizzoni

Medeiros

2017

ArqVet

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A imunohematologia veterinária vem ganhando interesse nos últimos anos devido a maior acessibilidade a tecnologias de detecção de antígenos e anticorpos, interesse dos donos e médicos veterinários em buscar uma melhor qualidade de vida para os animais e as necessidades de transfusões com o menor índice possível de reações indesejadas. Os cães possuem antígenos presentes na membrana de suas células vermelhas, podendo causar reações durante e após transfusões. Diferentemente de humanos e felinos, cães não possuem anticorpos naturais para os principais antígenos, a priori podendo ser transfundidos com qualquer tipo sanguíneo sem consequências posteriores, porém, se submetidos a uma segunda transfusão, sendo essa de um tipo sanguíneo incompatível e previamente sensibilizados, as chances de ocorrer reações transfusionais graves aumentam drasticamente, ocasionando danos ao animal, podendo levá-lo à morte. Por conta desses riscos se faz necessário uma maior atenção aos tipos sanguíneos desses animais onde 8 sistemas são reconhecidos internacionalmente classificados como sistema DEA, sendo eles DEA 1 e seus subtipos (DEA 1.1; DEA1.2; DEA 1.3); DEA 3; DEA 4; DEA 5; DEA 6; DEA 7 e DEA 8, e recentemente um novo sistema denominado Dal. Não há disponível ainda soros para os sistemas DEA 6 e DEA 8, tornando a pesquisa sobre esses antígenos dificultosa.

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“…Clinical severity of hemolysis can range from mild and well compensated to a life-threatening crisis. 3 Transfused RBCs may be susceptible to the same cause of hemolysis as native RBCs. Often changes in RBC shape are absent except for anisocytosis, signifying a regenerative anemia.…”

Section: Heritable Hemolysismentioning

confidence: 99%

Acute Hemolytic Disorders

Cohn¹

2015

Small Animal Critical Care Medicine

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Transfusion Medicine in Small Animal Practice

Cited by 66 publications

References 18 publications

Triggers, risk factors and clinico‐pathological features of urticaria in dogs – a prospective observational study of 24 cases

Triggers, risk factors and clinico‐pathological features of urticaria in dogs – a prospective observational study of 24 cases

Imunohematologia Veterinária: Antígenos Eritrocitários Caninos

Acute Hemolytic Disorders

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