Transformative Binding and Release of Gold Guests from a Self‐Assembled Cu₈L₄ Tube

Metal–organic container molecules through subcomponent self-assembly

“…The self-assembly of 6-methyl-2-formylpyridine, tetramine K and [Cu(MeCN)] 4 BF 4 resulted in the formation of [Cu 8 L 4 ] 8+ host 25. 111 In solution 25 exists as two isomers with approximate D 2d and D 4 point symmetries, both of which could be isolated In seeking thermodynamic equilibrium, this host-guest system is observed not only to stabilise an otherwise inaccessible guest, but to generate an optimal guest from amongst the different possibilities latent in the system. Host molecule 25 showed a remarkable selectivity for KAu(CN) 2 over a wide range of other linear potential guests…”

Supramolecular coordination chemistry

“…In another study, a tubular Cu 8 L 4 array was accessed using the subcomponent self-assembly of L 88 with copper ions. 68 Of the two diastereoisomers formed, the D 4 symmetric isomer was shown to selectively bind Au(CN) 2…”

Guest Controlled Nonmonotonic Deep Cavity Cavitand Assembly State Switching

“…Manipulating self-assembly to form discrete, structurally well-defined supramolecular complexes − offers an efficient way to engender compartmentalization and hence bring about novel approaches to controlling the spatial position of atoms. As a result, compartmentalization can be used to organize matter and broaden the utility of X-ray crystallography, , control chemical reactivity and catalysis, ,− and bring about novel separation protocols. − Of the varied strategies used for driving the assembly of molecular containers, utilizing the hydrophobic effect is arguably the least explored, yet offers a route not just to the formation of container complexes, but also into the complex relationship between solute shape, solvation, and the hydrophobic effect writ large. , …”