Transferring a poor quality embryo with a good quality embryo benefits poor prognosis patients: a retrospective study using propensity score matching

Abstract

Objective: To evaluate the effect of transferring a poor quality embryo (PQE) with a good quality embryo (GQE) on the outcomes in poor prognosis patients. Design: Retrospective cohort study. Setting: University-affiliated hospital. Population: A total of 5,037 FBT cycles between January 2012 and May 2019. Methods: Single FBT with GQE were defined as group G and double FBT with GQE plus PQE were defined as group GP. Propensity score matching was applied to control for potential confounders. Multivariate generalized estimating equations (GEE) models were used to identify the association between the effect of an additional PQE and outcomes. Main Outcome Measures: Live births and multiple pregnancies. Results: Group GP resulted in a significantly higher live birth rate (LBR) than group G in women aged 35 and over and in women who received over 3 cycles of embryo transfer (ET) (48.