Transfer of Phosphate in the Digestive Tract III. Dairy Cattle

Smith, Arthur H.; Kleiber, Max; Black, Arthur L.; Lofgreen, G. P.

doi:10.1093/jn/58.1.95

Cited by 27 publications

(24 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This finding is in disagreement with earlier reports by other workers (Scarisbrick & Ewer, 1951;Parthasarathy, 1952;Smith et al 1955;Pfeffer, 1968;Scott, McLean & Buchan, 1984a, b). The net flux of inorganic phosphate across the wall in vivo was linearly related to the phosphate concentration in the lumen although the regression lines obtained for P-replete and P-depleted sheep were different from each other.…”

Section: Discussioncontrasting

confidence: 96%

“…Comparisons of P concentrations in rumen fluid and venous blood (Parthasarathy, 1952;Parthasarathy, Garton & Phillipson, 1952) and between arterial and venous blood draining the reticulo-rumen (Yano, Sekiya, Kawashima & Kumada, 1978) did not indicate any significant phosphate passage. Injection of the tracer 32P either into the rumen (Scarisbrick & Ewer, 1951;Parthasarathy et al 1952;Wright, 1955;Pfeffer, 1968) or intravenously Smith, Kleiber, Black & Baxter, 1955) showed that the rumen epithelium was permeable to phosphate in both directions though all authors agree that only insignificant amounts of phosphate appear to move across the wall.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

FLUX OF INORGANIC PHOSPHATE ACROSS THE SHEEP RUMEN WALL IN VIVO AND IN VITRO

Breves¹,

Höller²,

Packheiser³

et al. 1988

Exp Physiol

View full text Add to dashboard Cite

SUMMARYExperiments were done in vivo and in vitro to study the flux of inorganic phosphate (Pi) across the rumen wall in sheep. The technique of the temporarily isolated and washed reticulo-rumen was applied to measure Pi net flux at nine different Pi concentrations in the buffer solutions introduced into the reticulo-rumen for 1 h. Six sheep were either P replete (4-25 g P d-l) or in a P-depleted state (1-05 g P d-1). Under both dietary treatments Pi net secretion into the reticulorumen was found at Pi concentrations between 0 1 and 2-2 mmol 1-1 whereas Pi net absorption was observed at P, concentrations between 4-1 and 15 8 mmol 1-1. There

show abstract

Section: Discussioncontrasting

confidence: 96%

Section: Introductionmentioning

confidence: 99%

FLUX OF INORGANIC PHOSPHATE ACROSS THE SHEEP RUMEN WALL IN VIVO AND IN VITRO

Breves¹,

Höller²,

Packheiser³

et al. 1988

Exp Physiol

View full text Add to dashboard Cite

show abstract

“…Values given by Tribe & Peel (1963) were used to calculate the total salivary P secretion; those of Adams & Heath (1963) were used for the biliary contribution. Similar values were not found for the other secretions; but, from the earlier work done in this laboratory (Smith, Kleiber, Black & Baxter, 1955;Smith, Kleiber, Black & Lofgreen, 1956) using 32P, it might be concluded that only small quantities of the element are secreted into the gastro-intestinal tract distal to the abomasum in the mature ruminant. This may contrast with the immature ruminant or young milkfed calf, in which the small intestine plays a greater part in the total intestinal secretion (Lofgreen, Kleiber & Smith, 1952;Chandler & Cragle, 1962).…”

Section: Vol 20supporting

confidence: 69%

The effects of phosphorus depletion, and of calcium and phosphorus intake, on the endogenous excretion of these elements by sheep

1966

View full text Add to dashboard Cite

I . Injections of and 45Ca were used to study the influence of phosphorus depletion and repletion on the rates of endogenous calcium and P excretion in fifteen P-depleted and eighteen control sheep. 2. When given adequate P, there was a marked increase in the rate of excretion of metabolic faecal P in sheep which previously had been depleted. In control sheep a decrease was found in metabolic faecal P excretion with a diet deficient in P. 3. From the values for metabolic faecal P an indirect estimate of total intestinal secretion was made. The estimate was found to be in approximate agreement with values derived from published values for total daily digestive secretions in sheep. 4. The estimated rates of secretion of intestinal P suggest that after the addition of P to the diet the changes in the rate of excretion of metabolic faecal P in P-depleted sheep were the result of a decreased reabsorption of intestinally secreted P rather than of a change in the rate of secretion into the intestine. After a diet low in this element the decrease in metabolic faecal P excretion by control sheep appeared to be the result of a decreased rate of intestinal P secretion. 5 . The possible significance of changes in metabolic faecal P excretion in relation to body P homoeostasis in the ruminant animal is discussed.The physiological significance of endogenous faecal calcium and phosphorus excretion is not clear. Moreover, the question of whether there is a controlled secretion of these elements into the intestinal tract, regulating their concentration in the body, has been disputed for years. The current general consensus, as indicated in recent reviews (Hill, 1963 ;Irving, 1964), is that the excretions of Ca and P are not controlled, but instead represent a loss of these elements in the digestive juices and turnover of the intestinal mucosa.

show abstract

“…This indicates that intestinal phosphate absorption is similar in ruminating lambs, in which large amounts of phosphate enter the digestive tract via the large volume of secreted saliva (Watson, 1933;Smith, Kleiber, Black & Baxter, 1955;Kay, 1960;Tomas, Moir & Somers, 1967;Compton, Nelson, Wright & Young, 1980;Mafias-Almendros, Ross, R. & Care, 1982;Scott, McLean & Buchan, 1984b) and in milk-fed lambs, where probably much less phosphate is secreted by the salivary glands. Unfortunately data on phosphate secretion by the salivary glands are not available for milk-fed lambs, but it has been shown that much less phosphorus enters the digestive tract via the saliva in milk-fed calves compared to cattle (Smith, Kleiber, Black & Lofgreen, 1956;Boehncke, Langner & Weissmann, 1981;Gropp, Kdnig, Feuchter & Muller, 1982). The transport mechanisms of the intestinal epithelium for phosphate therefore do not seem to adjust to the increasing influx of endogenous phosphate into the digestive tract during rumen development.…”

Section: Discussionmentioning

confidence: 91%

Phosphate Absorption at Different Intestinal Sites in the Developing Lamb

Scharrer

1985

Exp Physiol

View full text Add to dashboard Cite

SUMMARYNet phosphate absorption was studied at different sites of the intestine in milk-fed lambs of different age (1 week, 3-4 weeks, 10-13 weeks) and also in lambs fed a solid diet (age: 10-13 weeks). Disappearance of phosphate from ligated intestinal segments filled or perfused with an electrolyte solution containing 1.2 mmol/l phosphate was employed as measure for phosphate absorption. In all groups of animals the mid-jejunum absorbed phosphate with the greatest velocity. In the 1-week-old lambs the proximal colon descendens was almost as efficient, though phosphate absorption at this site was minimal in the other groups of animals. With the exception of the distal jejunum, phosphate absorption appeared to decrease with age. Between animals of the same age fed either a liquid milk diet or a solid diet phosphate absorption did not differ significantly. Phosphate absorption from the mid-jejunum was inhibited by galactose and glucose in the 1-week-old lambs. The significance of these findings in relation to control of phosphate absorption in the developing lamb is discussed.

show abstract

Transfer of Phosphate in the Digestive Tract III. Dairy Cattle

Cited by 27 publications

References 0 publications

FLUX OF INORGANIC PHOSPHATE ACROSS THE SHEEP RUMEN WALL IN VIVO AND IN VITRO

FLUX OF INORGANIC PHOSPHATE ACROSS THE SHEEP RUMEN WALL IN VIVO AND IN VITRO

The effects of phosphorus depletion, and of calcium and phosphorus intake, on the endogenous excretion of these elements by sheep

Phosphate Absorption at Different Intestinal Sites in the Developing Lamb

Contact Info

Product

Resources

About