Transfer of a grapevine stilbene synthase gene to rice (Oryza sativa L.)

Stark-Lorenzen, P.; Nelke, B.; Hänssler, G.; Mühlbach, Hans‐Peter; Thomzik, J. E.

doi:10.1007/s002990050299

Cited by 149 publications

(70 citation statements)

References 24 publications

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“…To allow the synthesis of stilbene synthase in tobacco, rape, tomatoes, potatoes, and rice, the gene coding for stilbene synthase has been engineered into these plant species. 7 Increased resistance to fungal infections was observed in these transgenic plants. 7 resverAtrol ActIvIty on cell lInes Introductory considerations.…”

Section: Resveratrol a Plant Phytoalexinmentioning

confidence: 98%

Resveratrol: From Basic Science to the Clinic

Cucciolla¹,

Borriello²,

Oliva³

et al. 2007

Cell Cycle

158

102

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Plants produce an extraordinary array of low molecular mass natural products endowed with biological activity. Among these molecules, resveratrol (3,5,4'-trihydroxystilbene) has been identified as an inhibitor of carcinogenesis with a pleiotropic mode of action. Extensive literature on its anticancer activity, performed in cellular models, suggests a potential antiproliferative and apoptogenic use of the stilbene. Similarly, studies on implanted cancers and chemical-induced tumors confirm a potential chemotherapeutical interest of the compound. Moreover, recent intriguing studies have demonstrated, in mice, that the negative effects (insulin resistance and hyperglycemia) of a high-fat diet might be prevented by resveratrol treatment. Despite these promising observations, only few clinical trials have been performed on the compound due to the scarce interest of pharmaceutical industry. We suggest that resveratrol might be considered an interesting anticancer compound in association with more specific target-oriented drugs.

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Section: Resveratrol a Plant Phytoalexinmentioning

confidence: 98%

Resveratrol: From Basic Science to the Clinic

Cucciolla¹,

Borriello²,

Oliva³

et al. 2007

Cell Cycle

158

102

View full text Add to dashboard Cite

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“…In addition, the expression of a stilbene synthase gene increased resistance to B. cinerea in transgenic tobacco, barley, and wheat plants (Hain et al, 1993;Leckband and Lorz, 1998;Serazetdinova et al, 2005). Furthermore, Stark-Lorenzen et al (1997) reported that rice plants transformed with the grapevine stilbene synthase gene exhibited enhanced resistance against the rice blast pathogen P. oryzae. However, in transformed tomato, the stilbene synthase gene did not enhance resistance against B. cinerea (Kobayashi et al, 2000).…”

Section: Resultsmentioning

confidence: 93%

“…Plant breeders are still trying to develop rice cultivars having high quality and quantity value. Nowadays, genetic engineering is among the various methods being used to enhance nutritional or functional value of rice plants, and confer resistance to pathogens (Stark-Lorenzen et al, 1997;Ye et al, 2003).…”

Section: Introductionmentioning

confidence: 99%

Disease Occurrence in Transgenic Rice Plant Transformed with Silbene Synthase Gene and Evaluation of Possible Horizontal Gene Transfer to Plant Pathogens

Yu¹,

Jeong²,

Lee³

et al. 2014

Research in Plant Disease

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Genetic engineering is being used to enhance disease resistance and nutritional value of crops including rice plant. Considering the fast-growing agricultural biotechnology and rapidly increasing global area of transgenic crops, the risk evaluation on environment is necessary. In this study, we surveyed the difference of disease occurrence between transgenic rice variety, Iksan526 transformed with peanut stilbene synthase gene and non-transgenic rice varieties, Dongjin and Nampyeong in the field. Moreover, the possibility of gene transfer from transgenic rice to bacterial and fungal pathogens was investigated. The results of this study indicated that there was no significant difference in the occurrence and severity of the diseases between Iksan526 and Dongjin or Nampyeong. In addition, the results suggested that rice pathogen, such as Xanthomonas oryzae pv. oryzae, Rhizoctonia solani and Magnaporthe grisea did not take up stilbene synthase and bar genes under natural conditions. Moreover the transformed DNA was not transferred to the pathogens even in repetitive contacts.

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“…The expression of this gene was first noted in sorghum seedlings infected with Colletotrichum sublineolum (Lo et al 2002). A fast accumulation of stilbene synthase-specific mRNA followed by a decrease was also obtained in transgenic tobacco (Hain et al 1993) and transgenic rice (Stark-Lorenzen et al 1997). Marked increase in barley occurred after 48 h, but was not observed in transgenic tobacco and rice.…”

Section: Discussionmentioning

confidence: 91%

“…The effectiveness of stilbene synthase genes in increasing resistance in transgenic tomatoes was shown by a 65% reduction in disease incidence following inoculation with the pathogen Phytophthora infestans . Results from transgenic rice plants indicated that the stilbene synthase gene enhanced plant resistance against the rice blast fungal pathogen Pyricularia oryzae (Stark-Lorenzen et al 1997).…”

Section: Discussionmentioning

confidence: 99%

Defense gene expression in Sorghum bicolor against Macrophomina phaseolina in leaves and roots of susceptible and resistant cultivars

Sharma

Kumari

Sharma

2013

Journal of Plant Interactions

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The fungal disease, charcoal root rot, caused by Macrophomina phaseolina is a foremost yield restraining factor of Sorghum bicolor L. around the world. The expression analysis of genes induced in general defense response can endow with clues to reveal major defense mechanisms against pathogen infection in sorghum plant. The role of chitinase and Stilbene synthase in response to M. phaseolina in sorghum was studied under control growth conditions using a real-time polymerase chain reaction. Here, we report the expression analysis of antifungal genes in two cultivars viz. PJ-1430 (resistant) and SU-1080 (susceptible) at different hours after inoculation with M. phaseolina isolate MTCC 2165. Chitinase and stilbene synthase were induced in PJ-1430 within 0 h, 24 h and in SU-1080 in 48 h, 24 h, respectively, after inoculation. However, the expression levels of chitinase and stilbene synthase in resistant cultivar were significantly higher. The results showed that chitinase and stilbene synthase can be effective to enhance resistance to M. phaseolina.

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Transfer of a grapevine stilbene synthase gene to rice (Oryza sativa L.)

Cited by 149 publications

References 24 publications

Resveratrol: From Basic Science to the Clinic

Resveratrol: From Basic Science to the Clinic

Disease Occurrence in Transgenic Rice Plant Transformed with Silbene Synthase Gene and Evaluation of Possible Horizontal Gene Transfer to Plant Pathogens

Defense gene expression in Sorghum bicolor against Macrophomina phaseolina in leaves and roots of susceptible and resistant cultivars

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