Transfer Hydrogenation of Ketones Catalysed by New Half‐Sandwich Ruthenium(II) Complexes Bearing the Sulfonated Phosphane (meta‐Sulfonatophenyl)diphenylphosphane Potassium Salt (TPPMS)

Abstract

-arene = p-cymene (2a), benzene (2b)] containing the water-soluble (meta-sulfonatophenyl)diphenylphosphane potassium salt (TPPMS) have been synthesised. The X-ray analysis for complex 1a revealed that, in the solid state, complex anions are held together in the crystal lattice by weak electrostatic interactions with potassium cations leading to a linear chain structure. The extent of the association in solution depends on the solvent and the determination of the size of the particles in THF can be accomplished using Multiangle Light Scattering

Arene-ruthenium(ii) complexes with hydrophilic P-donor ligands: versatile catalysts in aqueous media

“…On the other hand, the catalytic performances of complexes [RuCl 2 (η 6 -arene)(TPPMS)] (arene = C 6 H 6 (2a), p-cymene (2b)) and their bis-phosphine counterparts [RuCl(η 6 -arene)-(TPPMS) 2 ]Cl (arene = C 6 H 6 (3a), p-cymene (3b)) were explored in the transfer hydrogenation of several aromatic and aliphatic ketones, using 2-propanol as the solvent and the hydrogen source (Scheme 4). 27 In all the cases, the resulting alcohol was generated in good yield in the presence of KOH. Turnover frequencies of up to 2982 h −1 were achieved with the best catalysts, namely [RuCl 2 (η 6 -arene)(TPPMS)] (2a-b).…”

Water‐Soluble Phenanthroline Complexes of Rhodium, Iridium and Ruthenium for the Regeneration of NADH in the Enzymatic Reduction of Ketones

“…As there is a risk of slow hydrolysis in water, the aqueous solutions are immediately filtered, and the filtrates are concentrated to dryness to give the analytically pure salts [1][2][3][4]Cl. All compounds have been characterised by 1 H and 13 C NMR spectroscopy, mass spectroscopy and elemental analysis.…”

“…Transfer hydrogenation of NAD + to NADH in aqueous solution catalysed by cationic chlorido complexes 1 to 5 by using the formate anion as the hydrogen source. [36] the new 5-nitro-and 5-amino-1,10-phenanthroline cations 2, 3 and 4 are chiral, and compounds [2]Cl, [3]Cl and [4]Cl are produced as racemic mixtures.…”

“…[1] The transition-metal-based enantioselective hydrogenation or transfer hydrogenation of ketones in organic solvents [2][3][4][5][6][7][8][9][10] as well as in aqueous solutions [11][12][13][14][15][16][17][18][19][20][21] is one of the most commonly used synthetic approaches. Biotransformations of organic substrates by various enzymes have also found widespread applications, particularly because of their capability to efficiently perform enantioselective transformations.…”

High‐Yield Synthesis and Crystal Structure Determination of Sodium Triphenylphosphane Monosulfonate (TPPMSNa)

“…This property might be especially helpful in the development of metal complexes in biphasic catalysis. [9][10][11] Experimental Section General: TPPDS [12] and TPPTS, [13] used as reference materials, were synthesized according to literature methods. NMR spectra were recorded with a Bruker Avance DRX 200 and a Bruker Avance DRX 500 spectrometer.…”