Transfer Factor in the Treatment of B-Cell Disorders: Effects and Potential Risks

Silverman, Michael A.; Meltz, Susan K.; Yanovich, Saul; Mansell, Peter W.A.; Lessner, Howard E.; Hensley, George T.; Sorokin, Carol F.; Glade, Philip R.

doi:10.1016/b978-0-12-406060-9.50050-2

Cited by 3 publications

(2 citation statements)

References 5 publications

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“…There have been some suggestions in the literature that transfer factor might effect B cell function [17] and cause changes in the immunoglobulin levels. In the present report, transfer factor treatment failed to cause signi ficant changes in the immunoglobulin levels of the patients who had been treated for up to 6 months.…”

Section: Discussionmentioning

confidence: 99%

Transfer Factor in the Treatment of Herpes Simplex Types 1 and 2

Khan¹,

Hansen²,

Hill³

et al. 1981

Dermatology

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Transfer factor potentiates cellular immunity and induces interferon. It was because of these properties that transfer factor was tried in 17 patients with recurrent herpes simplex types 1 and 2. Transfer factor was administered in doses ranging from 5 to 10 U/m2 i.m. The interval between injections varied from 1 week to 3 months. 16 patients could be evaluated clinically in whom the recurrence rate decreased from 10.7 ± 6.1 to 2.1 ± 2.5 (mean SD). The reduction was statistically significant. 8 patients were completely free of disease while the other 8 had a reduced number of episodes during the period of observation. 7 patients had abnormal T cell function as reflected by the low number of T cells or low lymphocyte transformation. Statistically significant improvement in the T cell function was observed. Delayed hypersensitivity skin test reactions also improved significantly.

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Section: Discussionmentioning

confidence: 99%

Transfer Factor in the Treatment of Herpes Simplex Types 1 and 2

Khan¹,

Hansen²,

Hill³

et al. 1981

Dermatology

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“…ФП застосовується при дуже широкому спектрі вірусних інфекцій -сьогодні це одна з основних сфер його використан ня в клініці. Серед них: СНІД [64][65][66], вірус Bullosa simplex [67 ], вірус Епштейна-Барр на фоні онкологічного процесу [68][69][70] та при хронічному захворюванні [71 ], енцефаліт (на тваринній мо делі) [72,73], гепатит [74--78], герпес [79][80][81] [69,96 ], хворобі Ходжкіна [98][99][100][101], аденокарциномі (у поєднанні з БЦЖ чи хіміопрепаратами) [102][103][104], злоякісних новоут вореннях сечового міхура [105][106][107], пухлинах простати [108][109][110], дитячій лейкемії [111], пух линах молочної залози [112,113], макроглобулінемії та генералізованій меланомі [114], епідер мальній карциномі [115]…”

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Transfer factor as modulator of cellular immune response

1997

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Transfer Factor

Kirkpatrick

Burger

1980

CRC Critical Reviews in Clinical Laboratory Sciences

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The understanding of passive transfer of cell mediated-immune responses with transfer factor and other cell free materials has progressed to the point that investigators are seeking the chemical identity of the molecule(s) that are responsible for these effects and are working on their mechanisms of action. In addition, clinical trials are underway that should clarify the potential for use of transfer factor in treatment of infections, neoplastic and autoimmune diseases. This chapter will critically review the past and current data concerning the components of transfer factor and their effects on immunologic and inflammatory reactions. Some of the recently developed animal models will be described and evaluated, and the clinical studies that have provided conclusive data regarding efficacy will be reviewed.

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Transfer Factor in the Treatment of B-Cell Disorders: Effects and Potential Risks

Cited by 3 publications

References 5 publications

Transfer Factor in the Treatment of Herpes Simplex Types 1 and 2

Transfer Factor in the Treatment of Herpes Simplex Types 1 and 2

Transfer factor as modulator of cellular immune response

Transfer Factor

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