Transepithelial Elimination of Cutaneous Chromomycosis

Batres, Enrique; Wolf, John E.; Rudolph, Andrew H.; Knox, John M.

doi:10.1001/archderm.1978.01640200083027

Cited by 65 publications

(11 citation statements)

References 8 publications

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“…In our study it was used in only 18 of 51 cases with the predominant process being tuberculoid granuloma, with marked acanthosis and pseudoepitheliomatous hyperplasia as well as abundant giant cells which might contain parasitic elements. Sclerotic bodies were easily identified with the usual haematoxylin‐eosin stain; no special stains were required since their dark colour makes them stand out quite well [1, 4, 18, 19].…”

Section: Discussionmentioning

confidence: 99%

Chromoblastomycosis: clinical and mycologic experience of 51 cases

Bonifáz

Carrasco‐Gerard

Saúl

2001

Mycoses

188

166

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This is a study of 51 cases of chromoblastomycosis detected in a 17-year period, all of which were clinically and mycologically proven by direct examinations, cultures and biopsies. The therapeutic results of the various treatments used are reported. Most cases were males (36 of 51; 70%), the mean age was 35 years and farmers predominated (74%); the most frequent lesions were in the lower limbs (54%). Major clinical presentations were nodular (41%) and verrucous (26%). The principal aetiologic agent isolated was Fonsecaea pedrosoi (90%). Overall results of the various treatments were as follows: 31% were cured, 57% improved and 12% failed. The best results were obtained with cryosurgery for small lesions, with itraconazole for large ones, and in some cases the combination of both treatments.

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Section: Discussionmentioning

confidence: 99%

Chromoblastomycosis: clinical and mycologic experience of 51 cases

Bonifáz

Carrasco‐Gerard

Saúl

2001

Mycoses

188

166

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“…600 Intraepidermal abscesses are frequently observed, with or without fungal cells (Fig. 606 Dematia-C. neoformans has been traditionally classified into three varieties with five serotypes: C. neoformans var. 600 Occasionally, the fungal bodies can be seen between keratinocytes; this has been referred to as transepithelial elimination.…”

Section: Chromoblastomycosismentioning

confidence: 99%

Skin Infections

Prieto-Granada¹,

Lobo²,

Mihm³

2010

Diagnostic Pathology of Infectious Disease

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“…Biopsy is very useful. There is usually a granulomatous For reprint orders, please contact: reprints@ashley-pub.com process with transepithelial elimination and presence of muriform cells [1,3,7,8].…”

Section: Introductionmentioning

confidence: 99%

“…A series of therapeutic options have been proposed through the years, ranging from physical ones, such as surgery, to the recent oral antifungals. In general, the therapeutic decision depends upon a series of conditions, such as extension; type of lesions; clinical topography; causal agent; and the status of the patient [1,[4][5][6][7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Treating chromoblastomycosis with systemic antifungals

Bonifáz

Paredes-Solis

Saúl

2004

Expert Opinion on Pharmacotherapy

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Chromoblastomycosis is a subcutaneous mycosis for which there is no treatment of choice but rather, several treatment options, with low cure rates and many relapses. The choice of treatment should consider several conditions, such as the causal agent (the most common one being Fonsecaea pedrosoi ), extension of the lesions, clinical topography and health status of the patient. Most oral and systemic antifungals have been used; the best results have been obtained with itraconazole and terbinafine at high doses, for a mean of 6 - 12 months. In extensive and refractory cases, chemotherapy with oral antifungals may be associated with thermotherapy (local heat and/or cryosurgery). Limited or early cases may be managed with surgical methods, always associated with oral antifungal agents. It is important to determine the in vitro sensitivity of the major causal agents to the various drugs, by estimating the minimum inhibitory concentration, as well as drug tolerability and drug interactions.

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Transepithelial Elimination of Cutaneous Chromomycosis

Cited by 65 publications

References 8 publications

Chromoblastomycosis: clinical and mycologic experience of 51 cases

Chromoblastomycosis: clinical and mycologic experience of 51 cases

Skin Infections

Treating chromoblastomycosis with systemic antifungals

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