Transduodenal surgical ampullectomy: a procedure that requires a multidisciplinary approach

Mola, Fabio F. di; Panaccio, Paolo; Grottola, Tommaso; Bonis, Antonio De; Sapia, Giovanni; Farrukh, Maira; Sebastiano, Pierluigi Di

doi:10.1007/s13304-020-00951-y

Cited by 5 publications

(3 citation statements)

References 42 publications

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“…Concerns regarding radicality are justified as demonstrated by Nappo et al (39) who reported a 13.0% rate of R1 resections with TDA. Similarly, di Mola et al (46) in a recent paper reported a 28.5% rate of R1 resections up to T2 AT with TDA.…”

Section: Tdamentioning

confidence: 66%

From endoscopic resection to pancreatoduodenectomy: a narrative review of treatment modalities for the tumors of the ampulla of Vater

Taliente¹,

Bianco²,

Moschetta³

et al. 2022

Chin Clin Oncol

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Background and Objective: Tumors of the ampulla of Vater are a rare set of lesions that arise at the confluence of the common bile duct (CBD) and the pancreatic duct. They can be benign or malignant, often not easy to discriminate before treatment. Malignant tumors have low chances of survival (overall 5-year survival between 0% and 60%) and surgery is still the only curative option. Prognostic factors are being investigated to tailor therapeutic approach and improve outcomes. Due to their location in a complex anatomical region, all treatment options are challenging and associated with relevant morbidity. In this review we discuss different excisional techniques for the treatment of ampullary tumors (AT).Methods: A review of medical databases (PubMed and Google Scholar) was conducted selecting most relevant articles in English language without a specific timeframe. After first selection, most relevant citations were identified through snowballing.Key Content and Findings: Pancreatoduodenectomy (PD) is the gold standard in malignant tumors, achieving the most radical treatment, at the price of worse perioperative morbidity/mortality and quality of life. Trans-duodenal ampullectomy (TDA) was developed before endoscopic resection (ER) and maintains a role only in selected patients. ER is now the first choice for benign lesions and expanding towards early stages malignant AT.Conclusions: Pancreatodudenectomy remains the best option for the radical excision of malignant AT, recently being offered also via minimally invasive approach. However, in early-stage malignant tumors, ER is gaining importance with foreseeable further expansion. Transduodenal ampullectomy still has a role in selected patients, such as unfit for PD when ER is not possible mainly due to anatomical abnormalities.

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Section: Tdamentioning

confidence: 66%

From endoscopic resection to pancreatoduodenectomy: a narrative review of treatment modalities for the tumors of the ampulla of Vater

Taliente¹,

Bianco²,

Moschetta³

et al. 2022

Chin Clin Oncol

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“…Die transduodenale Ampullektomie repräsentiert das Verfahren mit der geringsten Invasivität. Wenngleich das operative Vorgehen durch Halsted 1899 24 erstmals beschrieben wurde, so ist seine Akzeptanz insgesamt gering gewesen. Gegenwärtig sind überwiegend monozentrische, retrospektive Analysen veröffentlicht 10 , 25 – 27 , die recht unterschiedliche Angaben zur Morbidität (10,5 – 64%) aufweisen.…”

Section: Chirurgische Therapieunclassified

Duodenaladenome und -karzinome: chirurgische Therapiekonzepte

Ghadimi¹,

Gaedcke²

2022

Allgemein- und Viszeralchirurgie up2date

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“…Die transduodenale Ampullektomie repräsentiert das Verfahren mit der geringsten Invasivität. Wenngleich das operative Vorgehen durch Halsted 1899 24 erstmals beschrieben wurde, so ist seine Akzeptanz insgesamt gering gewesen. Gegenwärtig sind überwiegend monozentrische, retrospektive Analysen veröffentlicht 10 , 25 , 26 , 27 , die recht unterschiedliche Angaben zur Morbidität (10,5 – 64%) aufweisen.…”

Section: Chirurgische Therapieunclassified

Duodenaladenome und -karzinome: chirurgische Therapiekonzepte

Ghadimi¹,

Gaedcke²

2022

Onkologie up2date

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Transduodenal surgical ampullectomy: a procedure that requires a multidisciplinary approach

Cited by 5 publications

References 42 publications

From endoscopic resection to pancreatoduodenectomy: a narrative review of treatment modalities for the tumors of the ampulla of Vater

From endoscopic resection to pancreatoduodenectomy: a narrative review of treatment modalities for the tumors of the ampulla of Vater

Duodenaladenome und -karzinome: chirurgische Therapiekonzepte

Duodenaladenome und -karzinome: chirurgische Therapiekonzepte

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