Transdermal delivery of sinapine thiocyanate by gelatin microspheres and hyaluronic acid microneedles for allergic asthma in guinea pigs

Thiocyanate promoted difunctionalization and cyclization of unsaturated C–C bonds to construct 1-sulfur-2-nitrogen-functionalized alkenes and 2-thiocyanate indolines

“…1 They are also important synthetic intermediates for obtaining valuable sulphur-containing compounds, especially for the synthesis of organosulfur compounds such as thiols, sulphur ethers and sulphides, and a safe source of cyanide for the formation of C–CN bonds. 2 In addition, thiocyanates can be used as sulfur and nitrile nucleophiles to construct biologically active heterocycles such as pyrimidines and thiazoles. 3 Meanwhile, isothiocyanate is not only an intermediate for the synthesis of antimicrobial and medically active substances, but also an organic dye for the immunoglobulin biomarker.…”