Transcutaneous electrical nerve stimulation on ST36 and SP6 acupoints prevents hyperglycaemic response during anaesthesia: a randomised controlled trial

Man, K. Ching; Man, Samantha S; Shen, Jui-Lung; Law, Kim-Seng; Chen, Shun-Liang; Liaw, Wen‐Jinn; Lee, Chao-Te; Lee, Yuan-Ju; Liao, Wen‐Ling; Chang, Tzu-Ming; Yu, Dexin; Chen, Der-Cherng; Chen, Yung‐Hsiang; Chen, Wen‐Chi; Chang, Shih‐Liang

doi:10.1097/eja.0b013e32833fad52

Cited by 19 publications

(22 citation statements)

References 30 publications

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“…An earlier study showed that the application of TENS to the ST36 and SP6 acupoints can prevent hyperglycemic responses during anesthesia. Researchers found that TENS can significantly decrease plasma glucose levels, insulin levels, and the HOMA index in the experimental group compared with the placebo group after the use of TENS during preoperative elective hysterectomy [13]. Thus, TENS may be considered a new treatment modality for plasma glucose control and insulin activity enhancement before surgery.…”

Section: Resultsmentioning

confidence: 99%

Acupoint‐Specific, Frequency‐Dependent, and Improved Insulin Sensitivity Hypoglycemic Effect of Electroacupuncture Applied to Drug‐Combined Therapy Studied by a Randomized Control Clinical Trial

Lin

Tzeng

Lee

et al. 2014

Evidence-Based Complementary and Alternative Medicine

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The application of electroacupuncture (EA) to specific acupoints can induce a hypoglycemic effect in streptozotocin-induced rats, normal rats, and rats with steroid-induced insulin resistance. EA combined with the oral insulin sensitizer rosiglitazone improved insulin sensitivity in rats and humans with type II diabetes mellitus (DM). There are different hypoglycemic mechanisms between Zhongwan and Zusanli acupoints by EA stimulation. On low-frequency (2 Hz) stimulation at bilateral Zusanli acupoints, serotonin was involved in the hypoglycemic effect in normal rats. Moreover, after 15 Hz EA stimulation at the bilateral Zusanli acupoints, although enhanced insulin activity mainly acts on the insulin-sensitive target organs, the muscles must be considered. In addition, 15 Hz EA stimulation at the bilateral Zusanli acupoints has the combined effect of enhancing cholinergic nerve activity and increasing nitric oxide synthase (NOS) activity to enhance insulin activity. Despite the well-documented effect of pain control by EA in many systemic diseases, there are few high-quality long-term clinical trials on the hypoglycemic effect of EA in DM. Combination treatment with EA and other medications seems to be an alternative treatment to achieve better therapeutic goals that merit future investigation.

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Section: Resultsmentioning

confidence: 99%

Acupoint‐Specific, Frequency‐Dependent, and Improved Insulin Sensitivity Hypoglycemic Effect of Electroacupuncture Applied to Drug‐Combined Therapy Studied by a Randomized Control Clinical Trial

Lin

Tzeng

Lee

et al. 2014

Evidence-Based Complementary and Alternative Medicine

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“…Acupuncture may alleviate the stress response by balancing the sympathetic tone. EA at ST36 and SP6 for 30 min before induction prevented hyperglycaemia during anaesthesia, 52 and the increased levels of cortisone and increased sensitivity to insulin were attenuated. 48 52 Patients with some refractory complications may choose acupuncture as a potentially effective and non-invasive therapy.…”

Section: Other Complicationsmentioning

confidence: 90%

Perioperative acupuncture modulation: more than anaesthesia

Lü

Dong

Wang

et al. 2015

British Journal of Anaesthesia

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Accumulated evidences from clinical trials and updated reviews suggest that the role of acupuncture in perioperative medicine extends beyond the classical scope of anaesthesia and has been underestimated. Perioperative acupuncture reduces not only the consumption of anaesthetics and analgesics, but also anaesthesia-related complications, and protects organs in the perioperative period. These beneficial effects make acupuncture a promising approach in perioperative management, especially with respect to enhanced surgery recovery and specific surgical populations, such as elderly patients and 'triple-low' patients. Furthermore, efforts have been made to optimize the clinical application of perioperative acupuncture.

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“…In another recent RCT, the effect of transcutaneous electrical nerve stimulation (TENS) on acupuncture points on serum glucose, serum insulin, and insulin resistance during surgical anesthesia for elective hysterectomy was measured in 60 women without diabetes [55]. In this study, participants were randomized to either TENS treatment that received 30 min of electrical stimulation or placebo, in which the electrical contact pads were placed on the points but were not stimulated electrically.…”

Section: Acupuncture and Related Therapiesmentioning

confidence: 99%

Complementary and Alternative Medicine in Diabetes Care

et al. 2012

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Growing numbers of people with diabetes in the U.S. and worldwide use complementary and alternative medicine (CAM) while receiving conventional medical therapy as a means of managing disease and improving quality of life. Although herbal and natural products are the most commonly used forms of CAM, mind-body approaches are also gaining popularity and scientific interest. Current findings suggest that CAM may help to promote an integrative, participatory model of diabetes care that relies upon provider knowledge of evidence-based therapies and patient disclosure of CAM use. Emerging evidence of positive findings with some natural products and mind-body therapies have been reported in glycemic parameters, markers of cardiovascular risk, and quality of life in individuals with type 2 diabetes; however, further investigation in well-designed, adequately powered studies is needed before use of CAM modalities can be recommended as part of clinical care.

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Transcutaneous electrical nerve stimulation on ST36 and SP6 acupoints prevents hyperglycaemic response during anaesthesia: a randomised controlled trial

Abstract: We found TENS at bilateral ST36 and SP6 acupoints to be an alternative means of managing the plasma glucose level and improving insulin resistance perioperatively.

Cited by 19 publications

References 30 publications

Acupoint‐Specific, Frequency‐Dependent, and Improved Insulin Sensitivity Hypoglycemic Effect of Electroacupuncture Applied to Drug‐Combined Therapy Studied by a Randomized Control Clinical Trial

Acupoint‐Specific, Frequency‐Dependent, and Improved Insulin Sensitivity Hypoglycemic Effect of Electroacupuncture Applied to Drug‐Combined Therapy Studied by a Randomized Control Clinical Trial

Perioperative acupuncture modulation: more than anaesthesia

Complementary and Alternative Medicine in Diabetes Care

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