2021
DOI: 10.1016/j.surg.2021.08.007
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Transcutaneous electrical acupoint stimulation applied in lower limbs decreases the incidence of paralytic ileus after colorectal surgery: A multicenter randomized controlled trial

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Cited by 27 publications
(20 citation statements)
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“… 32 The mechanism was also found in a human study that transcutaneous electrical acupoint stimulation applied in the lower limbs enhanced gastrointestinal functional recovery, which is associated with increased parasympathetic nerve tone and its anti-inflammatory actions. 33 Considering that most of the existing studies are aimed at lower limb acupoints, and the efficacy and underlying mechanisms of acupoints in the abdomen or limbs may be different, further research focusing on determining the specific mechanism of action is required.…”
Section: Discussionmentioning
confidence: 99%
“… 32 The mechanism was also found in a human study that transcutaneous electrical acupoint stimulation applied in the lower limbs enhanced gastrointestinal functional recovery, which is associated with increased parasympathetic nerve tone and its anti-inflammatory actions. 33 Considering that most of the existing studies are aimed at lower limb acupoints, and the efficacy and underlying mechanisms of acupoints in the abdomen or limbs may be different, further research focusing on determining the specific mechanism of action is required.…”
Section: Discussionmentioning
confidence: 99%
“…The primary outcome was the first postoperative flatus time, and the secondary outcomes were the first postoperative defecation time and the incidence rates of abdominal distension, abdominal pain, nausea, and vomiting within 3 days postoperatively. In our previous clinical study ( Gao et al, 2021 ), the patients and their caregiving family members were required to accurately record the first time of occurrence of the symptoms mentioned above by filling out the patient assessment forms, which would be transcribed on an evaluation sheet in the case report form (CRF) by researchers. If the patient did not have flatus within 3 days after the operation, the researchers would continue to follow-up by telephone until the first flatus time was obtained.…”
Section: Methodsmentioning
confidence: 99%
“…POGD is a transient impairment of gastrointestinal function after abdominal surgery and is manifested as delayed flatus and defecation, nausea, vomiting, abdominal tenderness, and abdominal distention ( Mazzotta et al, 2020 ). The occurrence of POGD prolongs hospitalization time and increases treatment costs enormously ( Vather et al, 2013 ; Murphy et al, 2016 ; Gao et al, 2021 ). Various strategies have been used to prevent POGD, including early postoperative feeding, avoidance of nasogastric tube use, limitation of fluid infusion, the use of minimally invasive surgery, and the use of symptomatic treatment drugs and chewing gum, but their effectiveness is limited because of the lack of pathogenesis-related targeted therapies ( Bragg et al, 2015 ; Wolthuis et al, 2016 ; Wang et al, 2020 ; Wattchow et al, 2021 ).…”
Section: Introductionmentioning
confidence: 99%
“…Clinical studies showed that nondrug therapy6 and complementary and alternative therapies,7 especially acupuncture and acupoint stimulation therapy,8,9 can significantly relieve CRF. Transcutaneous electrical acupoint stimulation (TEAS) intervention can facilitate neuron regeneration and neurotrophin secretion, increase muscle strength and activity, and improve a variety of accompanying symptoms and quality of life 10–12. However, TEAS treatment is completely dependent on doctors, and the relevant medical resources are in shortage.…”
mentioning
confidence: 99%
“…Transcutaneous electrical acupoint stimulation (TEAS) intervention can facilitate neuron regeneration and neurotrophin secretion, increase muscle strength and activity, and improve a variety of accompanying symptoms and quality of life. [10][11][12] However, TEAS treatment is completely dependent on doctors, and the relevant medical resources are in shortage. Moreover, because the treatment protocols are not universal and because patients have limited self-awareness towards their own condition, recovery can hardly be continued and the treatment is ineffective.…”
mentioning
confidence: 99%