Transcutaneous detection of relative changes in artery diameter

Hoeks, A.P.G.; Ruissen, C.J.; Hick, P.; Reneman, Robert S.

doi:10.1016/0301-5629(85)90007-9

Cited by 83 publications

(38 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This trigger was also used to mark the start of the cardiac cycle when velocities were recorded. The relative artery diameter changes are independent of the angle of interrogation and can be determined with an absolute accuracy of 0.5%, 9 which compares favorably with the relative peak excursions observed. This means that for a relative excursion of, for example, 7%, a relative change in artery diameter of 6.5-7.5% can be measured.…”

Section: Methodsmentioning

confidence: 53%

“…This direction was used because the assessment of vessel wall displacement is based upon the detection of low-frequency Doppler signals originating from the sample volumes coinciding with the anterior and posterior walls. 9 To ensure that the initial relative change at the beginning of the cardiac cycle was constant, this initial relative change was reset to 0 by a trigger derived from the R-wave of a standard lead of the electrocardiogram. This trigger was also used to mark the start of the cardiac cycle when velocities were recorded.…”

Section: Methodsmentioning

confidence: 99%

“…4 However, these systems do not distinguish blood flow disturbances induced by minor lesions from the complex blood flow patterns in normal carotid bifurcations. Multigate pulsed Doppler systems also allow on-line recording of changes in artery diameter during the cardiac cycle, 9 giving insight into local artery wall properties along the carotid artery bifurcation. 8 ' 10 Since local changes in artery wall distensibility may be anticipated in atherosclerosis, information about these changes might eventually improve the accuracy of diagnosing minor atherosclerotic lesions.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Accurate noninvasive method to diagnose minor atherosclerotic lesions in carotid artery bulb.

Merode

Lodder

Smeets

et al. 1989

Stroke

View full text Add to dashboard Cite

In a prospective study using a multigate pulsed Doppler system, minor (<30% diameter reduction) carotid artery lesions were diagnosed by detecting not only abnormalities in the blood flow pattern, but also local changes in artery wall distensibility. For the diagnosis of more severe lesions, additional information was obtained from disturbances in the Doppler audio spectrum. Biplane arteriography was used as a reference. The observed agreement, sensitivity, and specificity were 86.6%, 90.3%, and 88.6%, respectively, for all lesions and 85.7%, 82.1%, and 88.6%, respectively, when only minor lesions were considered, K (a chance-corrected measure of agreement) was 81.7%. If only blood flow abnormalities were used to detect minor lesions, 43.5% would be missed. Our results indicate that minor carotid artery lesions can be diagnosed noninvasively more accurately when both local blood flow irregularities and local changes in vessel wall distensibility are taken into account. (Stroke 1989;20:1336-1340

show abstract

Section: Methodsmentioning

confidence: 53%

Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Accurate noninvasive method to diagnose minor atherosclerotic lesions in carotid artery bulb.

Merode

Lodder

Smeets

et al. 1989

Stroke

View full text Add to dashboard Cite

show abstract

“…After supine rest of 10 min, the left common carotid artery was studied 2 cm below the bifurcation using a multi-gate pulsed Doppler system. 13,14 The method is based upon the processing of low frequency Doppler signals originating from the sample volumes coinciding with the anterior and posterior vessel walls. The positions of the sample volumes are continuously adjusted according to the displacement of the wall.…”

Section: Methodsmentioning

confidence: 99%

A longitudinal study of vessel wall properties in normotensive and hypertensive renal transplant recipients

et al. 1998

View full text Add to dashboard Cite

The mechanisms responsible for reduced arterial distensibility in renal transplant recipients remain to be evaluated. The present longitudinal study was aimed to evaluate the effect of hypertension on the evolution of vessel wall properties in renal transplant recipients. The mechanical properties of the common carotid artery were determined in 24 normotensive and 24 treated hypertensive renal transplant recipients 6-12 weeks after transplantation. The measurements were repeated after 2 years. Arterial distension was determined by using a multigate pulsed Doppler system, blood pressure (BP) was measured by a mercury sphygmomanometer. BP was 127 ؎ 3/80 ؎ 2 mm Hg at entry and 133 ؎ 3/82 ؎ 2 mm Hg after 2 years in the normotensive group, 146 ؎ 4/90 ؎ 3 mm Hg at entry and 145 ؎ 3/87 ؎ 2 mm Hg after 2 years in the hypertensive group (P Ͻ 0.01, normotensives vs hypertensives). The distens-

show abstract

“…The velocity profiles at discrete time intervals during the cardiac cycle, the instantaneous velocity tracings along the ultrasound beam, and the relative diameter perpendicular to plane bifurcation l based on the detection of low-frequency Doppler signals originating from the sample volumes coinciding with the anterior and posterior walls. 10 To ensure that the initial relative change at the beginning of the cardiac cycle was constant, it was reset to zero by a trigger derived from the R wave of a standard lead of the electrocardiogram. This trigger was also used to mark the start of the cardiac cycle when velocities were recorded.…”

Section: Methodsmentioning

confidence: 99%

Flow velocity patterns in and distensibility of the carotid artery bulb in subjects of various ages.

Reneman¹,

Merode²,

Hick³

et al. 1985

Circulation

149

View full text Add to dashboard Cite

Velocity patterns in and distensibility of the carotid artery bulb were studied in younger (20 to 30 years; n -1 1) and older (50 to 60 years; n 9) volunteers without detectable lesions of the cervical carotid arteries by means of a high-resolution, multigate, pulsed Doppler system coupled to a B mode imager. In the bulb the axial velocities were highest on the side of the flow divider, while regions of flow separation and recirculation were observed on the side opposite to this divider. Flow separation and recirculation were less pronounced and less common in the older subjects. Flow separation was not continuously present throughout the cardiac cycle. The distensibility of the carotid arteries was significantly diminished in older subjects, especially in the bulb. The velocity patterns in the carotid artery bulb of younger subjects corroborate the patterns observed in models. The diminished flow separation and recirculation in the older subjects might result from alterations in distensibility at the transition from common to internal carotid artery with increasing age. Circulation 71, No. 3, 500-509, 1985. IN A RECENT STUDY relating data derived from autopsy specimens to flow patterns and shear stresses as assessed in model bifurcation, . ' 2Zarins et al.3 showed that in the carotid artery bulb, maximal intimal thickening and atherosclerotic plaque formation occurred in regions of flow separation and reduced shear stress. These regions were located on the side opposite to the flow divider. Regions with predominantly axial and unidirectional flow velocities and high shear stresses, located on the side of the flow divider, were relatively devoid of these wall changes. A zone of recirculation in the carotid artery bulb opposite to the flow divider was also observed in studies performed on excised human carotid artery bifurcations.4 In these investigations flow patterns were studied under conditions of steady flow, while undistensible materials and Newtonian fluids were used, conditions quite different from the situation in vivo. Although preliminary studies in models indicate that the flow patterns in the carotid artery bulb are similar under steady and pulsaFrom the

show abstract

Transcutaneous detection of relative changes in artery diameter

Cited by 83 publications

References 8 publications

Accurate noninvasive method to diagnose minor atherosclerotic lesions in carotid artery bulb.

Accurate noninvasive method to diagnose minor atherosclerotic lesions in carotid artery bulb.

A longitudinal study of vessel wall properties in normotensive and hypertensive renal transplant recipients

Flow velocity patterns in and distensibility of the carotid artery bulb in subjects of various ages.

Contact Info

Product

Resources

About