Transcutaneous bilirubinometry: Its role in the assessment of neonatal jaundice

Dai, Jian; Parry, David M.; Krahn, John

doi:10.1016/s0009-9120(96)00131-2

Cited by 53 publications

(35 citation statements)

References 53 publications

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“…Other studies have generally demonstrated that the JM meter readings are less accurate in babies with dark skin. 7 There are several applications for the TCB measurements. One is in a jaundiced infant to determine if serum bilirubin should be drawn to guide treatment.…”

Section: Discussionmentioning

confidence: 99%

Improved Transcutaneous Bilirubinometry: Comparison of SpectR X BiliCheck and Minolta Jaundice Meter JM-102 for Estimating Total Serum Bilirubin in a Normal Newborn Population

2002

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Section: Discussionmentioning

confidence: 99%

Improved Transcutaneous Bilirubinometry: Comparison of SpectR X BiliCheck and Minolta Jaundice Meter JM-102 for Estimating Total Serum Bilirubin in a Normal Newborn Population

2002

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“…A noninvasive alternative to visual inspection is the use of instruments that measure bilirubin transcutaneously (8 -20 ). Transcutaneous bilirubin (TcB) 3 concentrations correlate with laboratory measurement, but they may underestimate the serum bilirubin, particularly when concentrations are Ͼ171 mol/L (13,14 ). Despite this shortcoming, the use of TcB to screen newborns for hyperbilirubinemia has been suggested as a fast, reasonable alternative to laboratory-based bilirubin testing (8 -10, 13, 14, 18 ).…”

Section: Evidence-based Laboratory Medicine and Test Utilizationmentioning

confidence: 99%

Association of Transcutaneous Bilirubin Testing in Hospital with Decreased Readmission Rate for Hyperbilirubinemia

et al. 2005

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Background: Newborns are being discharged from hospitals within 1-2 days of birth, before hyperbilirubinemia usually becomes clinically evident. We investigated the use of transcutaneous bilirubin (TcB) before discharge to determine whether it affects the use of laboratory bilirubin testing or decreases the number of neonates readmitted for hyperbilirubinemia within 7 days of initial discharge. Babies who did not fit the diagnosis-related group criteria of "normal newborn" were removed, leaving 6933 babies who were included in the study. April was considered a transition month and was not included in the study, leaving 6603 newborns to be included. Of these, 446 (6.8%) required phototherapy for treatment of hyperbilirubinemia before initial discharge. For the 8 months before and 8 months after initiation of TcB testing, the number of

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“…Thirty-two separate studies in infants from different population groups concluded that transcutaneous readings are correlated with plasma bilirubin. 40 The equation relating the two is population and bilirubin method dependent. For meters such as the Minolta Airshields JM102, the regression equation must be established by each centre for its own population and bilirubin methodology.…”

Section: First-line Assessment Of Jaundice Transcutaneous Monitorsmentioning

confidence: 99%

“…41 Precision studies for transcutaneous monitors used cuvettes containing bilirubin solutions, or a small number of repeat measurements on an infant over a short timeperiod. 40 The reported studies have generally been carried out as part of a research protocol on a limited number of subjects. It is possible that the CIs of the correlation with plasma bilirubin could be even wider in routine practice.…”

Section: First-line Assessment Of Jaundice Transcutaneous Monitorsmentioning

confidence: 99%

Neonatal jaundice: a critical review of the role and practice of bilirubin analysis

Kirk

2008

Ann Clin Biochem

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Neonatal jaundice is common, and usually harmless, because of physiological jaundice or breast-feeding. In some neonates unconjugated bilirubin concentration, coupled with other risk factors, is sufficient to allow free bilirubin to cross the bloodbrain barrier and cause kernicterus. Another subgroup of infants is jaundiced because of elevated conjugated bilirubin; a marker for a number of pathological conditions. Bilirubin measurement must identify those infants at risk. Transcutaneous bilirubin measurement is increasingly used in healthy infants, especially before early discharge or at home, to assess the need for laboratory bilirubin measurement. Transcutaneous measurements are not covered by laboratory quality assessment schemes. Guidelines on management of neonatal jaundice utilize age in hours and other risk factors to define bilirubin action thresholds, which may be as low as 100 mmol/L for sick premature infants, whereas early discharged babies may only present after bilirubin concentrations are extremely high. Hence, there is a requirement for accurate total bilirubin measurement from ,100 to .500 mmol/L, with sufficient precision to assess the rate of bilirubin change with time. Babies presenting with late jaundice always require conjugated bilirubin measurement. It is of concern that many total and direct bilirubin automated kit methods suffer from haemolysis interference, while use of in-house methods or modification of commercial methods has virtually disappeared. External quality assessment has a vital role in providing data on different methods' performance, including accuracy, precision and susceptibility to interference. Laboratories should consider whether their adult bilirubin methods are suitable for neonates.

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Transcutaneous bilirubinometry: Its role in the assessment of neonatal jaundice

Cited by 53 publications

References 53 publications

Improved Transcutaneous Bilirubinometry: Comparison of SpectR X BiliCheck and Minolta Jaundice Meter JM-102 for Estimating Total Serum Bilirubin in a Normal Newborn Population

Improved Transcutaneous Bilirubinometry: Comparison of SpectR X BiliCheck and Minolta Jaundice Meter JM-102 for Estimating Total Serum Bilirubin in a Normal Newborn Population

Association of Transcutaneous Bilirubin Testing in Hospital with Decreased Readmission Rate for Hyperbilirubinemia

Neonatal jaundice: a critical review of the role and practice of bilirubin analysis

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