Transcriptomics Analysis Revealed Key Genes Associated with Macrophage Autophagolysosome in Male ApoE−/− Mice Aortic Atherosclerosis
Meirong Zhu,
Tongyu Jin,
Ding Wu
et al.
Abstract:Purpose
Atherosclerosis (AS) is the most common cause of cardiovascular and cerebrovascular diseases. However, the mechanisms underlying atherosclerotic plaque progression remain unclear. This study aimed to investigate the genes associated with the development of atherosclerosis in the aorta of ApoE
−/−
male mice, which could serve as novel biomarkers and therapeutic targets in interventions to halt plaque progression.
Methods
Eight-week-old … Show more
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