Transcriptome analysis of the tardigradeHypsibius exemplarisexposed to the DNA-damaging agent bleomycin
Yuki Yoshida,
Akiyoshi Hirayama,
Kazuharu Arakawa
Abstract:Tardigrades are microscopic animals that are renowned for their capabilities of tolerating near-complete desiccation by entering an ametabolic state called anhydrobiosis. However, many species also show high tolerance against radiation in the active state as well, suggesting cross-tolerance via the anhydrobiosis mechanism. Previous studies utilized indirect DNA damaging agents to identify core components of the cross-tolerance machinery; however, it was difficult to distinguish whether transcriptomic changes w… Show more
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