“…This is not in line with literature reporting sLe X to be mainly regulated by FUT6 in CRC as well as breast cancer ( 27 , 77 ). Interestingly, in AML cell lines, we found that (s)Le A/X antigen expression was positively correlated with FUT7 instead of FUT3/4 ( 78 ). We hypothesize that the biosynthesis of glycans might be regulated by different GTs in a disease- and tissue-specific manner.…”