Transcriptional networks in leaf senescence

Schippers, Jos H. M.

doi:10.1016/j.pbi.2015.06.018

Cited by 128 publications

(120 citation statements)

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“…In recent years, small gene-regulatory networks for senescence-associated transcription factors have been uncovered (Schippers, 2015). Here, we consider three of these, NAP, WRKY53, and ORE1, and for simplicity, we focus on linear networks controlled by each factor in relation to a specific phytohormone.…”

Section: Molecular Regulation Of Senescence Transcriptional Networkmentioning

confidence: 99%

Living to Die and Dying to Live: The Survival Strategy behind Leaf Senescence

et al. 2015

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ORCID ID: 0000-0001-7934-126X (J.H.M.S.).Senescence represents the final developmental act of the leaf, during which the leaf cell is dismantled in a coordinated manner to remobilize nutrients and to secure reproductive success. The process of senescence provides the plant with phenotypic plasticity to help it adapt to adverse environmental conditions. Here, we provide a comprehensive overview of the factors and mechanisms that control the onset of senescence. We explain how the competence to senesce is established during leaf development, as depicted by the senescence window model. We also discuss the mechanisms by which phytohormones and environmental stresses control senescence as well as the impact of source-sink relationships on plant yield and stress tolerance. In addition, we discuss the role of senescence as a strategy for stress adaptation and how crop production and food quality could benefit from engineering or breeding crops with altered onset of senescence.

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Section: Molecular Regulation Of Senescence Transcriptional Networkmentioning

confidence: 99%

Living to Die and Dying to Live: The Survival Strategy behind Leaf Senescence

et al. 2015

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“…Thus, the knowledge of mechanisms underlying leaf aging has profound implications in many biotechnological applications, including increasing plant productivity and preventing post-harvest loss during transportation and storage. Regulation of leaf senescence is a complex process controlled by developmental and environmental signaling pathways (Lim et al, 2007; Woo et al, 2013; Schippers, 2015). Many senescence-associated genes ( SAGs ) and transcription factors have been identified (Gepstein et al, 2003; Buchanan-Wollaston et al, 2005; Breeze et al, 2011; Guo and Gan, 2012).…”

Section: Introductionmentioning

confidence: 99%

POWERDRESS interacts with HISTONE DEACETYLASE 9 to promote aging in Arabidopsis

Chen

Lü

Mayer

et al. 2016

eLife

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Leaf senescence is an essential part of the plant lifecycle during which nutrients are re-allocated to other tissues. The regulation of leaf senescence is a complex process. However, the underlying mechanism is poorly understood. Here, we uncovered a novel and the pivotal role of Arabidopsis HDA9 (a RPD3-like histone deacetylase) in promoting the onset of leaf senescence. We found that HDA9 acts in complex with a SANT domain-containing protein POWERDRESS (PWR) and transcription factor WRKY53. Our genome-wide profiling of HDA9 occupancy reveals that HDA9 directly binds to the promoters of key negative regulators of senescence and this association requires PWR. Furthermore, we found that PWR is important for HDA9 nuclear accumulation. This study reveals an uncharacterized epigenetic complex involved in leaf senescence and provides mechanistic insights into how a histone deacetylase along with a chromatin-binding protein contribute to a robust regulatory network to modulate the onset of plant aging.DOI: http://dx.doi.org/10.7554/eLife.17214.001

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“…As the final phase of leaf development, senescence is an important biological process accompanying the cessation of photosynthesis, chlorophyll breakdown, leaf proteins degradation, amino acids removal, as well as the mobilization of nitrogen, carbon and other minerals [1,2,3,4]. Although senescence is necessary to maximize a plant’s resource use, premature or abnormal senescence induced by biotic and abiotic stress often causes a decrease in crop yield and produce quality, as well as a decline in shelf-life during postharvest transportation and storage [5,6,7].…”

Section: Introductionmentioning

confidence: 99%

“…During senescence, leaves undergo a series of programmed molecular changes mediated by senescence-associated genes ( SAGs ) [1,5,9], which in turn, are controlled by transcription factors (TFs) [3,7,9,10,11,12]. The Arabidopsis thaliana genome encodes ~2,000 TFs, among which more than 200 TFs are related to leaf senescence [10,13].…”

Section: Introductionmentioning

confidence: 99%

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BrWRKY65, a WRKY Transcription Factor, Is Involved in Regulating Three Leaf Senescence-Associated Genes in Chinese Flowering Cabbage

Fan

Tan

Shan

et al. 2017

IJMS

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Plant-specific WRKY transcription factors (TFs) have been implicated to function as regulators of leaf senescence, but their association with postharvest leaf senescence of economically important leafy vegetables, is poorly understood. In this work, the characterization of a Group IIe WRKY TF, BrWRKY65, from Chinese flowering cabbage (Brassica rapa var. parachinensis) is reported. The expression of BrWRKY65 was up-regulated following leaf chlorophyll degradation and yellowing during postharvest senescence. Subcellular localization and transcriptional activation assays showed that BrWRKY65 was localized in the nucleus and exhibited trans-activation ability. Further electrophoretic mobility shift assay (EMSA) and transient expression analysis clearly revealed that BrWRKY65 directly bound to the W-box motifs in the promoters of three senescence-associated genes (SAGs) such as BrNYC1 and BrSGR1 associated with chlorophyll degradation, and BrDIN1, and subsequently activated their expressions. These findings demonstrate that BrWRKY65 may be positively associated with postharvest leaf senescence, at least partially, by the direct activation of SAGs. Taken together, these findings provide new insights into the transcriptional regulatory mechanism of postharvest leaf senescence in Chinese flowering cabbage.

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Transcriptional networks in leaf senescence

Cited by 128 publications

References 48 publications

Living to Die and Dying to Live: The Survival Strategy behind Leaf Senescence

Living to Die and Dying to Live: The Survival Strategy behind Leaf Senescence

POWERDRESS interacts with HISTONE DEACETYLASE 9 to promote aging in Arabidopsis

BrWRKY65, a WRKY Transcription Factor, Is Involved in Regulating Three Leaf Senescence-Associated Genes in Chinese Flowering Cabbage

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