Abstract:Hepatitis C virus (HCV) is a major public health problem
that affects
more than 170 million people globally. HCV is a principal cause of
hepatocellular carcinoma (HCC) around the globe due to the high frequency
of hepatitis C infection, and the high rate of HCC is seen in patients
with HCV cirrhosis. TP53 is considered as a frequently altered gene
in all cancer types, and it carries an interferon response element
in its promoter region. In addition to that, the TP53 gene also interacts
with different HCV prote… Show more
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