Transcranial Doppler Screening in 50 Patients With Sickle Cell Hemoglobinopathies in Iran

Zamani, Susan; Haghighi, Afshin Borhan; Haghpanah, Sezaneh; Karimi, Mehran; Bordbar, Mohammadreza

doi:10.1097/mph.0000000000000890

Cited by 3 publications

(2 citation statements)

References 43 publications

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“…TCD can be used to detect the disease when it occurs in cerebral blood flow. Zamani et al [16] showed that TCD was better than EEG in identifying the diseased vessels, ischemic degree, and anatomical location. However, EEG may find the changes of brain wave in VBI patients from the perspective of electrophysiology.…”

Section: Discussionmentioning

confidence: 99%

Evaluation on the application of transcranial Doppler (TCD) and electroencephalography (EEG) in patients with vertebrobasilar insufficiency

Zheng

Wang

et al. 2020

J Orthop Surg Res

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Background To evaluate the diagnostic value of transcranial Doppler (TCD) and electroencephalography (EEG) in patients with vertebrobasilar insufficiency (VBI) during clinical diagnosis and treatment Methods Eighty patients diagnosed with VBI in our hospital from June 2018 to December 2019 were randomly selected as the observation group, and 80 healthy people who received physical examination in the same period were selected as the control group. The abnormal rate, main performance and results, and the peak velocity of blood flow and vertebrobasilar artery blood flow of the two groups were compared. Results The abnormal rate of EEG and TCD in VBI patients was 38.75% (31/80) and the 93.75% (75/80), respectively. In TCD examination, ACA, PCA, MCA, and VA of both sides of the observation group were higher than those of the control group, while BA was lower than that of the control group (P < 0.05). The Vs, Vd, and Vm on both sides of BA and VA in the observation group were lower than those in the control group, while PI and RI were higher than those in the control group (P < 0.05). Conclusions TCD examination is highly sensitive to the degree and pattern of cerebral ischemia in VBI patients. EEG examination will define the changes of brain cell function after cerebral ischemia. Therefore, EEG and TCD have their own advantages. The application of TCD and EEG can be considered in the early diagnosis, curative effect, and prognosis evaluation of VBI patients, so as to improve the accuracy of diagnosis and prognosis.

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Section: Discussionmentioning

confidence: 99%

Evaluation on the application of transcranial Doppler (TCD) and electroencephalography (EEG) in patients with vertebrobasilar insufficiency

Zheng

Wang

et al. 2020

J Orthop Surg Res

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“…These events result in tissue ischemia, which leads to acute and chronic pain as well as damage of different organs in the body 7 . The low prevalence of ischemic change in some patients may be partly explained by the higher Hb F percentage among them 8 . The sickle cell anemia (SCA) patients with high Hb F level, Southern Iran, India and Eastern Saudi Arabia have the benign clinical course 9,10 .…”

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confidence: 99%

Hemoglobinopathies in Iran: An Updated Review

Nasiri

Rahimi

Vaisi‐Raygani

2020

IJHOSCR

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Hemoglobinopathies are the most common single gene disorders (monogenic disorders) in the world population. Due to specific position of Iran and the presence of multi-ethnic groups in the country, there are many varieties in the molecular genetics and clinical features of hemoglobinopathies in Iran. Hemoglobinopathies include structural variants, thalassemias, and hereditary persistence of fetal hemoglobin. In this review, we look at the common structural variants in various parts of the country along with their hematological and clinical characteristics. Also, we discuss about the burden of the thalassemias in the country, different types, complications, molecular defects and therapy.

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Sickle Cell Disease and Stroke

Hirtz

Kirkham

2019

Pediatric Neurology

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Transcranial Doppler Screening in 50 Patients With Sickle Cell Hemoglobinopathies in Iran

Cited by 3 publications

References 43 publications

Evaluation on the application of transcranial Doppler (TCD) and electroencephalography (EEG) in patients with vertebrobasilar insufficiency

Evaluation on the application of transcranial Doppler (TCD) and electroencephalography (EEG) in patients with vertebrobasilar insufficiency

Hemoglobinopathies in Iran: An Updated Review

Sickle Cell Disease and Stroke

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