Transcranial Alternating Current Stimulation to Modulate Alpha Activity: A Systematic Review

Koninck, Béatrice P. De; Brazeau, Daphnée; Guay, Samuel; Babiloni, Alberto Herrero; Beaumont, Louis De

doi:10.1016/j.neurom.2022.12.007

Cited by 10 publications

(5 citation statements)

References 118 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To account for such variations, studies choose stimulation protocols that measure the IAF before the stimulation in the alpha range and use it as the frequency parameter of the stimulation. Yet, no consistent effects on spectral power modulation arises from stimulating at the IAF rather than a fixed frequency (De Koninck et al, 2023).…”

Section: Clinical Applicationmentioning

confidence: 99%

Normative characterization of age-related periodic and aperiodic activity in resting-state clinical EEG recordings

Leroy,

Bublitz,

von Dincklage

et al. 2024

Preprint

View full text Add to dashboard Cite

ObjectiveNon-invasive oscillatory brain stimulation techniques target the oscillatory activity of the brain and have several potential therapeutic applications in the clinical context. The aim of these analyses from clinical routine EEG recordings was to provide normative values of physiological age-related oscillatory (periodic) and non-rhythmic (aperiodic) activity.MethodsWe analyzed 532 EEGs of patients between 8 and 92 years of age. EEG segments were preprocessed, and the power spectrum was computed using a multitaper method. We decomposed the power spectrum into periodic (peak power, frequency, and bandwidth) and aperiodic (intercept and exponent) components. Linear regression models were used to investigate age-related changes in these parameters.ResultsWe observed significant global age-related changes in the periodic alpha (- 0.015 Hz/year) and gamma (+ 0.013 to + 0.031Hz/year) peak frequency as well as in the aperiodic exponent (- 0.003 to - 0.004 μV2/Hz/year). In the other parameters there were solely regional or no significant age-related changes.ConclusionsDecomposing the power spectrum into periodic and aperiodic components allows for the characterization of age-related changes.SignificanceThis study provides the first spectrum-wide normative characterization of age-related changes in periodic and aperiodic activity, relevant for non-invasive brain stimulation with alternating current targeting ongoing oscillatory activity.Highlights-Alpha peak frequency decreases with age, while gamma peak frequency accelerates.-Age-related changes in alpha and theta power result from a flattening of the aperiodic slope, not decreased oscillatory activity-Decomposing the EEG spectrum into periodic and aperiodic activity is essential when characterizing ongoing oscillatory activity

show abstract

Section: Clinical Applicationmentioning

confidence: 99%

Normative characterization of age-related periodic and aperiodic activity in resting-state clinical EEG recordings

Leroy,

Bublitz,

von Dincklage

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…Both NFT and tACS have shown some improvement in the alpha amplitude, sensory perceptivity, and cognitive performance. [ 14 - 24 ]…”

Section: Cortical Excitability and Pulsed Inhibitionmentioning

confidence: 99%

The electroencephalographic brainwave spectrum, mindful meditation, and awareness: Hypothesis

Deshmukh

2023

Int J Yoga

View full text Add to dashboard Cite

It is hypothesized that being mindfully aware is a spontaneous state of being. It is imbued with joy, peace and happiness. Such a state is periodically revealed during restful attentiveness or presence. It is also associated with spontaneous brain alpha activity of 8–13 Hz. In deep nonrapid eye movement sleep, there is synchronous delta activity at a coherent frequency of 0.1 Hz. Both of these brainwave ground states are spontaneous, calm and effortless. When any physical or mental effort is made, the alpha rhythm is desynchronized, and it is superposed by faster brain waves of beta (13–30 Hz) and gamma frequencies (30–150 Hz). This is associated with a stream of dualistic conscious experiences with contents. During deep sleep, delta activity is superposed by beta and gamma activity with microarousals resulting in dream experiences. During effortless, meditative awareness, the whole family of alpha rhythm is synchronized including (a) Occipital-parietal alpha with visual clarity, formless color, and the absence of visual imagery (b) Frontal eye-field alpha with relatively motionless eyes, and the absence of voluntary actions or plans to move the eyes in some direction, along with nonactive working memory, (c) Somatosensory alpha or Mu rhythm from the somatic motor-sensory cortex with the resultant stillness of the body including head, face, larynx, spine, hands and legs, (d) Mid-temporal auditory alpha with vocal quietness and internal verbal silence ( Maunam ) with a feeling of spontaneous silence and serenity, (e) Cingulate and precuneus alpha resulting in freedom from autobiographical memories and the sense of agency or ego. The insular cortex serves as a gatekeeper, a hierarchical controller to switch between conscious engagement or disengagement from the internal or the external world. It switches between the default mode network and the executive frontoparietal networks, between the sequential and the parallel modes of functioning. Mindful consciousness is local and dualistic, whereas mindful awareness is nonlocal and nondual.

show abstract

“…If migraine is primarily related to dysrhythmia, then it may be the case that alternating current stimulation (tACS) could be of benefit. tACS can be used to modulate alpha-band power (for a review see [ 252 ]). Importantly, tACS can be used to modify alpha-band oscillations and thus influence performance on a perceptual task [ 60 ].…”

Section: Treatmentsmentioning

confidence: 99%

Excitation-Inhibition Imbalance in Migraine: From Neurotransmitters to Brain Oscillations

O’Hare

Tarasi

Asher

et al. 2023

IJMS

View full text Add to dashboard Cite

Migraine is among the most common and debilitating neurological disorders typically affecting people of working age. It is characterised by a unilateral, pulsating headache often associated with severe pain. Despite the intensive research, there is still little understanding of the pathophysiology of migraine. At the electrophysiological level, altered oscillatory parameters have been reported within the alpha and gamma bands. At the molecular level, altered glutamate and GABA concentrations have been reported. However, there has been little cross-talk between these lines of research. Thus, the relationship between oscillatory activity and neurotransmitter concentrations remains to be empirically traced. Importantly, how these indices link back to altered sensory processing has to be clearly established as yet. Accordingly, pharmacologic treatments have been mostly symptom-based, and yet sometimes proving ineffective in resolving pain or related issues. This review provides an integrative theoretical framework of excitation–inhibition imbalance for the understanding of current evidence and to address outstanding questions concerning the pathophysiology of migraine. We propose the use of computational modelling for the rigorous formulation of testable hypotheses on mechanisms of homeostatic imbalance and for the development of mechanism-based pharmacological treatments and neurostimulation interventions.

show abstract

Transcranial Alternating Current Stimulation to Modulate Alpha Activity: A Systematic Review

Cited by 10 publications

References 118 publications

Normative characterization of age-related periodic and aperiodic activity in resting-state clinical EEG recordings

Normative characterization of age-related periodic and aperiodic activity in resting-state clinical EEG recordings

The electroencephalographic brainwave spectrum, mindful meditation, and awareness: Hypothesis

Excitation-Inhibition Imbalance in Migraine: From Neurotransmitters to Brain Oscillations

Contact Info

Product

Resources

About