Transcatheter Mitral Valve Replacement for Patients With Symptomatic Mitral Regurgitation

Müller, D.; Farivar, Robert Saeid; Jansz, P.; Bae, Richard; Walters, D.; Clarke, Andrew; Grayburn, Paul A.; Stoler, Robert C.; Dahle, Gry; Rein, Kjell Arne; Shaw, Marty; Scalia, G.; Guerrero, Mayra; Pearson, Paul J.; Kapadia, Samir; Gillinov, Marc; Pichard, Augusto D.; Corso, Paul J.; Popma, Jeffrey J.; Chuang, Michael L; Blanke, Philipp; Leipsic, Jonathon; Sorajja, Paul; Investigators, Tendyne Global Feasibility Trial

doi:10.1016/j.jacc.2016.10.068

Cited by 255 publications

(112 citation statements)

References 39 publications

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“…through puncture of the left ventricular apex), whereas others are deployed through a trans-septal (venous) approach, which would be ideal in highest risk patients [11,12,14,15]. Encouraging data have recently been provided by a feasibility study ( NCT02321514 ) about the effectiveness and safety of transapical TMVR using a self-expanding device in patients with native MR at high risk for cardiac surgery, resulting in NYHA functional class improvement with mild or no symptoms in 75% of patients and successful device implantation without cardiovascular mortality, stroke, and device malfunction in 86.6% of patients at 30-day follow-up [16]. …”

Section: Transcatheter Mitral Valve Procedures: When and How?mentioning

confidence: 99%

Preprocedural planning of transcatheter mitral valve interventions by multidetector CT: What the radiologist needs to know

Faggioni

Gabelloni

Accogli

et al. 2018

European Journal of Radiology Open

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Mitral regurgitation is the most common valve disorder in the Western world, and although surgery is the established therapeutic gold standard, percutaneous transcatheter mitral interventions are gaining acceptance in selected patients who are inoperable or at an exceedingly high surgical risk. For such patients, multidetector computed tomography (MDCT) can provide a wealth of valuable morphological and functional information in the preoperative setting. Our aim is to give an overview of the MDCT image acquisition protocols, post-processing techniques, and imaging findings with which radiologists should be familiar to convey all relevant information to the Heart Team for successful treatment planning.

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Section: Transcatheter Mitral Valve Procedures: When and How?mentioning

confidence: 99%

Preprocedural planning of transcatheter mitral valve interventions by multidetector CT: What the radiologist needs to know

Faggioni

Gabelloni

Accogli

et al. 2018

European Journal of Radiology Open

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“…Other (14). The valve was successfully implanted in 93% of patients with only one death at 30 days for a non-cardiac cause (hospital-acquired pneumonia).…”

Section: Rodrigo Mendirichaga 1 Vikas Singhmentioning

confidence: 99%

Intrepid steps towards clinical prime time

Mendirichaga

Singh

2018

J. Thorac. Dis.

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“…transcatheter mitral valve replacement (TMVR). Several devices for TMVR have been developed and the feasibility of both transapical and transseptal implantation has been reported in small case series or first human reports [26,27]. Although TMVR has not yet been clinically adopted after failed MitraClip, this technique may represent a likely future therapeutic option in patients with severe MR due to aborted MitraClip procedures (e.g., the inability to grasp the MV leaflets) or to treat iatrogenic lesions of the MV that occurred before clip deployment.…”

Section: Future Therapeutic Optionsmentioning

confidence: 99%

Strategies and Outcomes of Repeat Mitral Valve Interventions after Failed MitraClip Therapy

Grasso

Buccheri²,

Capodanno³

et al. 2017

Cardiology

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Percutaneous mitral valve repair (PMVR) with the MitraClip system (Abbott Vascular, Santa Clara, CA, USA) is a valid therapeutic option for patients with severe mitral regurgitation (MR) deemed to be at high or prohibitive surgical risk. Despite the reassuring data on efficacy and long-term durability of the procedure, the proportion of patients with residual or relapsing severe MR after MitraClip therapy is not negligible. In light of the detrimental prognostic impact of severe MR, repeat interventions are increasingly performed in clinical practice using different techniques. In high-risk settings, percutaneous procedures have proven to be effective and safe at reducing MR. Building on this, we sought to summarize the current landscape and clinical experience of reinterventions after failed MitraClip therapy, so as to assist physicians facing the clinical hurdle of proper treatment management after failed PMVR.

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Transcatheter Mitral Valve Replacement for Patients With Symptomatic Mitral Regurgitation

Cited by 255 publications

References 39 publications

Preprocedural planning of transcatheter mitral valve interventions by multidetector CT: What the radiologist needs to know

Preprocedural planning of transcatheter mitral valve interventions by multidetector CT: What the radiologist needs to know

Intrepid steps towards clinical prime time

Strategies and Outcomes of Repeat Mitral Valve Interventions after Failed MitraClip Therapy

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