Transcatheter closure of atrial septal defects in adults with the Amplatzer septal occluder

Abstract

Objective-To assess the eYcacy and complications of device occlusion of atrial septal defects in adults, using the Amplatzer septal occluder (ASO). Design-A prospective interventional study. Setting-Paediatric cardiology departments in two European teaching hospitals. Patients-The first 20 patients accepted for atrial septal defect device occlusion, on the basis of transoesophageal echocardiography. Sixteen patients had larger defects with right heart dilatation, while the primary indication for closure in four was a history of early paradoxical embolism. There were residual shunts in three patients at the end of the procedure, which were trivial (< 1 mm) as assessed by transoesophageal echocardiography, and persisted for more than six months in only one patient. Follow up ranged from 0.1-1.5 years (median 0.7). There have been no late complications. Conclusions-The ASO device can be used successfully to close selected oval fossa defects in adults, with minimal procedural morbidity and excellent early results. (Heart 1999;82:559-562) Interventions-Transcatheter

Transcatheter Closure of Interatrial Communications for Secondary Prevention of Paradoxical Embolism

“…9 -12 However, in a recent study by Windecker et al 13 using 5 different types of closure devices, the periprocedural complication rate was 10% in 78 patients, including embolization of device parts, periprocedural transient ischemic attack (TIA), or stroke caused by air embolism, cardiac tamponade, and retroperitoneal hematoma. Initial results with the Amplatzer occluder in children 14 -16 and adults 17 with ASD and PFO 18 were promising in terms of efficacy and safety.…”

Canadian Cardiovascular Society 2009 Consensus Conference on the management of adults with congenital heart disease: Shunt lesions

“…In patients with secundum ASD, percutaneous ASD closure is the most frequently used closure method, and offers results comparable with surgical closure (9,(27)(28)(29). The procedure is guided by either TEE or intracardiac echo.…”

Transcatheter closure of atrial septal defect using Amplatzer septal occluder in Chinese adults

“…Recently, Redington et al [14] reported their experience in transcatheter closure of ASD using ASO in 20 adults. Most of their patients were symptomatic with effort intolerance or paradoxical embolism while the majority of our patients were asymptomatic.…”