Transbronchial Cryobiopsy in Interstitial Lung Disease

Rodrigo, José Antonio Cascante; Cebollero, Pilar; Herrero, S. Lorenzo; Yagüe, Adriana; Echegoyen, Ana; Elizalde, Jesus M.; Hueto, Javier

doi:10.1097/lbr.0000000000000292

Cited by 36 publications

(24 citation statements)

References 21 publications

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“…Several pilot studies have described the use of a smaller 1.1-mm cryoprobe, which can be pulled through a sheath placed in the working channel of the bronchoscope, allowing the bronchoscope to stay in place during cryoprobe retrieval and decreasing the concerns for uncontrolled endobronchial bleeding [90,91]. However, it is unclear whether these smaller cryobiopsies will result in diagnostic yields similar to those described with larger probes [92].…”

Section: Which Cryoprobe Should Be Used and How Long Should The Freezmentioning

confidence: 99%

Transbronchial Cryobiopsies for the Diagnosis of Diffuse Parenchymal Lung Diseases: Expert Statement from the Cryobiopsy Working Group on Safety and Utility and a Call for Standardization of the Procedure

et al. 2018

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Transbronchial cryobiopsies (TBCB) have recently been introduced as a promising and safer alternative to surgical lung biopsy in the diagnostic approach to diffuse parenchymal lung diseases (DPLD). Despite a substantial and expanding body of literature, the technique has not yet been standardized and its place in the diagnostic algorithm of DPLD remains to be defined. In part, this reflects concerns over the diagnostic yield and safety of the procedure, together with the rapid spread of the technique without competency and safety standards; furthermore, there is a substantial procedural variability among centers and interventional pulmonologists. We report this expert statement proposed during the third international conference on “Transbronchial Cryobiopsy in Diffuse Parenchymal Lung Disease” (Ravenna, October 27–28, 2016), which formulates evidence- and expert-based suggestions on the indications, contraindications, patient selection, and procedural aspects of the procedure. The following 5 domains were reviewed: (1) what is the role of TBCB in the diagnostic evaluation of DPLD: patient selection; (2) pathological considerations; (3) contraindications and safety considerations; (4) how should TBCB be performed and in what procedural environment; and (5) who should perform TBCB. Finally, the existence of white paper recommendations may also reassure local hospital credentialing committees tasked with endorsing an adoption of the technique.

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Section: Which Cryoprobe Should Be Used and How Long Should The Freezmentioning

confidence: 99%

Transbronchial Cryobiopsies for the Diagnosis of Diffuse Parenchymal Lung Diseases: Expert Statement from the Cryobiopsy Working Group on Safety and Utility and a Call for Standardization of the Procedure

et al. 2018

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“…A further key topic was transbronchial cryobiopsy, which due to larger samples and good tissue quality without crush artefacts, is particularly helpful in histological diagnosis of interstitial lung diseases, in which forceps biopsies often fail [37, 38]. One multicentre prospective study evaluated the feasibility, safety and potential role of transbronchial cryobiopsy in the diagnosis of diffuse lung infiltrates in 17 mechanically ventilated patients [39].…”

Section: Group 14: Interventional Pulmonologymentioning

confidence: 99%

Clinical highlights from the 2016 European Respiratory Society International Congress

Kahn

Fregonese²,

Barrecheguren

et al. 2017

ERJ Open Res

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This article contains highlights and a selection of the scientific advances from the European Respiratory Society (ERS) Clinical Assembly (Assembly 1) and its six respective groups (Groups 1.1–1.6) that were presented at the 2016 ERS International Congress in London, UK. The most relevant topics for clinicians will be discussed, covering a wide range of areas including clinical problems, rehabilitation and chronic care, thoracic imaging, interventional pulmonology, diffuse and parenchymal lung diseases, and general practice and primary care. In this comprehensive review, the newest research and actual data will be discussed and put into perspective.

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“…Transbronchial lung cryobiopsy (TBLC) is a new diagnostic technique [92,[122][123][124][125][126]. Its diagnostic effectiveness and complication rates are varied and depend on the experience of the person performing the procedure [123,125,[127][128][129][130][131][132][133][134][135][136][137][138][139]. The mean mortality due to this diagnostic procedure only has been estimated at 0.2%, with less frequent sudden exacerbations than in the case of SLB (1.2% vs 6.1%).…”

Section: Introductionmentioning

confidence: 99%

Guidelines of the Polish Respiratory Society for Diagnosis and Treatment of Idiopathic Pulmonary Fibrosis

Piotrowski

Bestry²,

Białas

et al. 2020

Advances in Respiratory Medicine

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Transbronchial Cryobiopsy in Interstitial Lung Disease

Abstract: A transbronchial lung cryobiopsy using a flexible cryoprobe has a good diagnostic yield and might be an alternative to consider in cases of diffuse ILD in which a histologic sample is required for diagnosis. This technique could avoid a large number of surgical biopsies.

Cited by 36 publications

References 21 publications

Transbronchial Cryobiopsies for the Diagnosis of Diffuse Parenchymal Lung Diseases: Expert Statement from the Cryobiopsy Working Group on Safety and Utility and a Call for Standardization of the Procedure

Transbronchial Cryobiopsies for the Diagnosis of Diffuse Parenchymal Lung Diseases: Expert Statement from the Cryobiopsy Working Group on Safety and Utility and a Call for Standardization of the Procedure

Clinical highlights from the 2016 European Respiratory Society International Congress

Guidelines of the Polish Respiratory Society for Diagnosis and Treatment of Idiopathic Pulmonary Fibrosis

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