Transarterial embolization of giant liver hemangiomas associated with kasabach-merritt syndrome: a case report

Malagari, Katerina; Alexopoulou, Efthymia; Dourakis, Spyros P.; Kelekis, Alexios; Hatzimichail, K.; Sissopoulos, Athanasios; Delis, Spiros; Letsou, D.; Kelekis, Dimitrios

doi:10.1080/02841850701326917

Cited by 24 publications

(20 citation statements)

References 23 publications

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“…[13]). Hierbei sind in der Akutsituation neben einer raschen Korrektur der Gerinnungs störung therapeutisch die besten Erfah rungen mit einer transarteriellen Embo lisation des Hämangiomherdes beschrie ben [23]. Eine Resektion des Hämangioms kann dann ggf.…”

Section: Risiko Einer Ruptur Oder Blutungunclassified

Surgical therapy of benign liver tumors

Loss

Zülke

Obed

et al. 2008

Chirurg

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Benign liver tumors are being detected more frequently due to the widespread use of ultrasound and complementary methods and due to improvements in diagnostic accuracy. In the case of a reliable diagnosis of asymptomatic hemangioma or focal nodular hyperplasia surgery is not indicated. Hepatic adenoma of considerable size should be resected primarily based on the risk of rupture. Improvements in diagnostic imaging as well as the optimization of surgical procedures with extremely low complication rates permit an individualized management strategy founded on evidence-based algorithms. In the case of an equivocal diagnosis, we advocate low-risk tumor resection instead of tumor biopsy due to the inherent complication rates of hemorrhage or tumor-cell dissemination and possible misleading histology.

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Section: Risiko Einer Ruptur Oder Blutungunclassified

Surgical therapy of benign liver tumors

Loss

Zülke

Obed

et al. 2008

Chirurg

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“…As mentioned in Table 1, KMS secondary to liver hemangiomas [107] and Merkel cell cancer involving the face [108] has been successfully treated with TAE. Intralesional injection of absolute alcohol [97] and steroids [102] have also been reported as management strategies.…”

Section: Others Embolizationmentioning

confidence: 99%

“…In large tumors, TAE can be a useful bridge before surgery is attempted or until the systemic treatment becomes effective [43,101,102]. There are also multiple case reports of successful treated KMS with endovascular approaches [103][104][105][106].…”

Section: Others Embolizationmentioning

confidence: 99%

Clinical Review: Management of Adult Kasabach-Merritt Syndrome Associated with Hemangiomas

Master¹,

Kallam²,

Eo³

et al. 2017

J Blood Disord Transfus

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Kasabach-Merritt syndrome (KMS) consists of a clinical trial of capillary hemangioma, thrombocytopenia and disseminated intravascular coagulation. KMS occurs most commonly in the pediatric population, and its occurrence in adults is rare. Specific guidelines or randomized clinical trials guiding clinical management of KMS in adult patients are lacking. This manuscript provides a comprehensive review of KMS and discusses recent advances in the medical management of KMS. We also propose a systematic therapeutic approach which would serve as a guide in the management of adult patients with KMS caused by hemangiomas.

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“…El trasplante hepático se llevará a cabo en pacientes sintomáticos con lesiones irresecables o en caso de un hemangioma gigante con hemangiomatosis y asociados al síndrome de Kasabach-Merrit (15)(16)(17). En determinados casos se ha probado la eficacia de la embolización transarterial de los hemangiomas con mejoría rápida de la coagulopatía de consumo (18).…”

Section: Discussionunclassified