Transarterial Closed-Chest Left Ventricular Bypass for Desperate Heart Failure1

Zwart, Hans H.J.; Kralios, Alexandros C.; Kwan-Gett, C.S.; Backman, D K; Foote, Jonathon; Andrade, J.; Kolff, W J

doi:10.1159/000391811

Cited by 10 publications

(8 citation statements)

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“…In 1962, Dennis et al described a method in which left atrial blood withdrawal was performed via the internal jugular venous and the interatrial septal approach to supply blood to the femoral artery using a roller pump (3). In 1966, Zwart et al introduced a method of retrograde transaortic valvular left ventricular blood withdrawal (4). However, the percutaneous left ventricular assist technique did not yield the expected clinical results because of the difficulties and risks associated with the transinteratrial septal approach and the use of a ridged and large‐bore catheter.…”

Section: Discussionmentioning

confidence: 99%

Potentialities and Problems of a Novel Bilateral Ventricular Assist System Without Thoracotomy

et al. 2000

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Mechanical cardiac assistance can be critical in saving the lives of patients with acute cardiac failure. However, currently used methods of ventricular assistance require advanced technical knowledge and equipment, and only small numbers of patients can be provided with them. Our aim was to develop new cannulas to construct a less invasive biventricular assist system that would permit easy application without thoracotomy. We prepared 2 centrifugal pumps and 4 uniquely shaped cannulas and conducted experiments to investigate the potential and problems of the system. In the first experiment, the system was attached to 6 dogs with ventricular fibrillation to confirm whether our system could maintain cardiac output. In the second experiment, the system was installed for 3 days in 3 goats, and changes in aminotransferases, BUN, creatinine, and plasma free hemoglobin levels were examined. In Experiment 1, it was demonstrated that the system was able to maintain circulation in dogs. In Experiment 2, although the flow rate of the pumps was maintained over 3 days, increased hemolysis and deteriorating renal function were observed. Although these problems need to be solved, the system was still helpful in the management of acute biventricular failure for short periods and may be clinically useful in the near future.

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Section: Discussionmentioning

confidence: 99%

Potentialities and Problems of a Novel Bilateral Ventricular Assist System Without Thoracotomy

et al. 2000

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“…Parallel to the increasing cardiosurgical activities, research in this field was also intensified. This was due to operative stress on the heart and the influence of the heart-lung machine on circulation [22][23][24][25][26][27][28][29]. It was proven that, after cardiac surgery using extracorporeal circulation systems, about 10% of the patients were not immediately able to build up a sufficient heart-time-volume.…”

Section: Introductionmentioning

confidence: 99%

The Spindle Pump—A Nonpulsatile Blood Pump for Assisted Circulation

et al. 1990

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“…On the basis of studies with closed chest by-pass devices (2,3) and intraventricular blood pumps (4) that used catheters or cannulas with external diameters of 18 to 21 French gauge, the first PUCA pump model had the following configuration: internal diameter (ID) of catheter, 6 mm; catheter length, 120 cm; and pump volume, 100 ml. Postmortem studies of patients who died from cardiovascular diseases demonstrated that atherosclerotic processes narrowed the internal diameter of most peripheral arteries.…”

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confidence: 99%

“…The wave form as a result of optimal timing was clearly present in the pumping mode of 1: 1, but was seen at other pumping modes as well. Neither the wave form nor the pumping mode-related ventricular pressure patterns were present in studies with nonpulsatile intraventricular blood pumps (2,5).…”

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confidence: 99%

In Vitro Evaluation of the Influence of Pulsatile Intraventricular Pumping on Ventricular Pressure Patterns

et al. 1994

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The Pulsatile catheter (PUCA) pump consists of a single port membrane pump connected to an indwelling valved catheter. This so-called transarterial blood pump was originally designed to be introduced through a superficial artery into the left ventricular cavity to pump blood from the left ventricle into the ascending aorta. By introducing the catheter directly into the thoracic aorta or the pulmonary artery, the possibility is created of applying large-diameter catheter PUCA pumps as left, right, or biventricular assist devices (LVAD, RVAD, or BIVAD) without damaging any of the structures of the heart. The pump performance of an 8 mm PUCA pump prototype (internal diameter catheter, 8 mm; catheter length, 40 cm; stroke volume, 80 ml) was studied in a mock circulation to investigate the influence of pulsatile intraventricular pumping on ventricular pressure patterns. The pumping mode of the PUCA pump was changed from approximately 1:1 ([n + 1]:n) to 1:2 ([1/2n + 1]:n) and 1:3 ([1/3n + 1]:n) in relation to the frequency of a ventricle-simulating membrane pump. Apart from the pumping mode, timing of the PUCA pump driving system (ejection phase) seems to be crucial in obtaining optimal unloading of the ventricle.

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Transarterial Closed-Chest Left Ventricular Bypass for Desperate Heart Failure1

Cited by 10 publications

References 0 publications

Potentialities and Problems of a Novel Bilateral Ventricular Assist System Without Thoracotomy

Potentialities and Problems of a Novel Bilateral Ventricular Assist System Without Thoracotomy

The Spindle Pump—A Nonpulsatile Blood Pump for Assisted Circulation

In Vitro Evaluation of the Influence of Pulsatile Intraventricular Pumping on Ventricular Pressure Patterns

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