Trans-kingdom fungal pathogens infecting both plants and humans, and the problem of azole fungicide resistance
Alexandra Pintye,
Renáta Bacsó,
Gábor M. Kovács
Abstract:Azole antifungals are abundantly used in the environment and play an important role in managing fungal diseases in clinics. Due to the widespread use, azole resistance is an emerging global problem for all applications in several fungal species, including trans-kingdom pathogens, capable of infecting plants and humans. Azoles used in agriculture and clinics share the mode of action and facilitating cross-resistance development. The extensive use of azoles in the environment, e.g., for plant protection and wood… Show more
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