Introduction: Foreign body (FB) ingestion is frequently observed in surgical and endoscopic practice. They are often removed from the body cavities without causing any severe complications but occasionally they lead to serious damages. We report a case of a rosemary branch ingestion causing a duodenal and Inferior Vena Cava (IVC) perforation. Case Presentation: A 61 year-old man was admitted in ER with abdominal pain, vomiting and with a single episode of melaena. Vital parameters were stable. The abdomen was mildly distended but tender. Computed tomography (CT) scan revealed a foreign body in the second part of duodenum, passing through it, reaching and perforating the Inferior Vena Cava (IVC). An urgent Esophagogastroduodenoscopy (EGDS) confirmed the presence of a rosemary branch passing through the duodenum in correspondence of the lower duodenal knee. An emergency surgery with a median xifopubic laparotomy was performed. The foreign body removed firstly from the duodenum, then from IVC. No complication were observed in the postoperative period. Discussion: This case peculiarity was the paucisymptomatic presentation related to the severe lesion to the vessels and the bowel. Laparotomic approach was chosen to permit a secure and effective bleeding control. Probably the lack of symptoms, was due to the presence of an extended fibrotic reaction around the rosemary branch. Conclusion: Duodenal perforation and large vessels lesions due to foreign body ingestion are rare conditions that can lead to severe complications. Not withstanding the utilization of Computed Tomography (CT) scans and endoscopic procedures, the surgical management of bowel perforation induced by foreign bodies continues to present a formidable challenge. The optimal course of acting to ensure a favorable clinical outcome frequently relies upon the surgical approach adopted by the operating surgeon.