trans-bis(salicylaldoximato)copper(II) and its derivatives as antiproliferative and antineoplastic agents: a review

Antimicrobial Activity and Spectral, Magnetic and Thermal Studies of Some Transition Metal Complexes of a Schiff Base Hydrazone Containing a Quinoline Moiety

“…It may be suggested that the chelated complexes deactivate various cellular enzymes, which play a vital role in various metabolic pathways of these microorganisms. It has also been proposed that the ultimate action of the toxicant is the denaturation of one or more proteins of the cell, which as a result, impairs normal cellular process [1][2][3][4][5][6][7][8][9][10][11][12]22].…”

“…Interest in the study of Schiff base hydrazones has been growing because of their antimicrobial, anti-tuberculosis, and anti-tumour activity [1][2][3][4][5][6][7][8][9][10][11][12]. Schiff bases play an important role in inorganic chemistry, as they easily form stable complexes with most transition metal ions.…”

“…The development of the field of bioinorganic chemistry has increased the interest in Schiff base complexes, since it has been recognized that many of these complexes may serve as models for biologically important species [1][2][3][4][5]. Coordination compounds derived from aroylhydrazones have been reported to act as enzyme inhibitors and are useful due to their pharmacological applications [6][7][8][9][10][11][12]. In view of the importance of such hydrazones, we describe here the synthesis and characterization of Cu(II), Ni(II), Co(II), Mn(II), Fe(III) and UO 2 (VI) complexes of 7-chloro-4-(benzylidenehydrazo)quinoline (HL, Figure 1).…”

Antimicrobial, spectral, magnetic and thermal studies of Cu(II), Ni(II), Co(II), UO2(VI) and Fe(III) complexes of the Schiff base derived from oxalylhydrazide

“…The development of the field of bioinorganic chemistry has increased the interest in Schiff base complexes, since it has been recognized that many of these complexes may serve as models for biologically important species [2][3][4][5][6][7]. The remarkable biological activity of acid hydrazides, a class of Schiff base, their corresponding aroylhydrazones, and the dependence of their mode of chelation with transition metal ions present in the living system have been of significant interest [7][8][9][10][11][12][13][14]. The coordination compounds of hydrazide and aroylhydrazones have been reported to act as enzyme inhibitors and are useful due to their pharmacological applications.…”

“…Hydrazones derived from condensation of isonicotinic acid hydrazide with pyridine aldehydes have been found to show better antitubercular activity than INH. [13]. Tri-and terdentate Shiff bases may contain ONO or ONS donor atoms and their metal complexes may be monomeric, dimeric, trimeric or tetrameric with abnormal magnetic properties and characteristic structures [8 -16].…”