Tranexamic acid use in sarcoma surgery patients: A systematic review and meta‐analysis
Victoria Giglio,
Aaron Gazendam,
Hadia Farrukh
et al.
Abstract:IntroductionPerioperative bleeding increases morbidity and mortality in sarcoma patients. Tranexamic acid (TXA), an antifibrinolytic, is widely utilized in non‐sarcoma orthopaedic surgeries, but its adoption in sarcoma surgery is hindered by concerns about thrombotic events.MethodsSearches in Ovid MEDLINE, EMBASE, and CENTRAL were performed without date restrictions. Inclusion criteria encompassed sarcoma patients undergoing surgery with TXA intervention. Two authors independently screened studies, resolved co… Show more
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