Tramadol sensing in non-invasive biological fluids using a voltammetric electronic tongue and an electrochemical sensor based on biomimetic recognition

Diouf, Alassane; Aghoutane, Youssra; Burhan, Hakan; Şen, Fatih; Bouchikhi, Benachir; Bari, Nezha El

doi:10.1016/j.ijpharm.2020.120114

Cited by 30 publications

(7 citation statements)

References 75 publications

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“…Besides, urine samples analyses using VE-Tongue and pattern recognition methods show good discrimination, classification, and prediction results with scores above 95%. Correspondingly, both electro-analytical devices could be viable for monitoring drugs in biological matrices 10 .…”

Section: Hplc Methodsmentioning

confidence: 99%

Validated analytical methods for estimation of tramadol

Thangabalan¹,

Pakkiraiswamynaicker²,

Raman³

2022

World J. Bio. Pharm. Health Sci.

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Tramadol is an opioid pain medication used to treat moderate to moderately severe pain. When taken by mouth in an immediate-release formulation, the onset of pain relief usually begins within an hour. It is also available by injection. It is available in combination with paracetamol (acetaminophen). There are many reported analytical methods for estimation of Tramadol. The present work list outs the various analytical methods for the estimation of the drug.

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Section: Hplc Methodsmentioning

confidence: 99%

Validated analytical methods for estimation of tramadol

Thangabalan¹,

Pakkiraiswamynaicker²,

Raman³

2022

World J. Bio. Pharm. Health Sci.

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“…Tramadol is a member of the phenanthrene opium alkaloids [46], and unlike standard opioid analgesics, tramadol eases pain through inhibiting the re-uptake of norepinephrine and serotonin and increasing their release [47][48][49]. This strong painkiller is widely used for the treatment of postoperative, neuropathic, somatic and visceral pain and so forth throughout the world [50][51][52].…”

Section: Tramadolmentioning

confidence: 99%

Graphene-Based Electrochemical Sensors for Psychoactive Drugs

Boroujerdi

Paul

2022

Nanomaterials

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Sensors developed from nanomaterials are increasingly used in a variety of fields, from simple wearable or medical sensors to be used at home to monitor health, to more complicated sensors being used by border customs or aviation industries. In recent times, nanoparticle-based sensors have begun to revolutionize drug-detection techniques, mainly due to their affordability, ease of use and portability, compared to conventional chromatography techniques. Thin graphene layers provide a significantly high surface to weight ratio compared to other nanomaterials, a characteristic that has led to the design of more sensitive and reliable sensors. The exceptional properties of graphene coupled with its potential to be tuned to target specific molecules have made graphene-based sensors one of the most popular and well-researched sensing materials of the past two decades with applications in environmental monitoring, medical diagnostics, and industries. Here, we present a review of developments in the applications of graphene-based sensors in sensing drugs such as cocaine, morphine, methamphetamine, ketamine, tramadol and so forth in the past decade. We compare graphene sensors with other sensors developed from ultrathin two-dimensional materials, such as transition-metal dichalcogenides, hexagonal boron nitrate, and MXenes, to measure drugs directly and indirectly, in various samples.

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“…MIP sensors have been used in determination of pain medications. Diouf et al ( 2021 ) described the use of MIP sensors to detect tramadol in spiked saliva and urine. Tramadol (TRA) is a weak opioid analgesic that is used to treat mild to moderately severe pain.…”

Section: Mip In Bioanalysismentioning

confidence: 99%

Recent molecularly imprinted polymers applications in bioanalysis

Suzaei¹,

Daryanavard

Abdel-Rehim

et al. 2022

Chem. Pap.

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Molecular imprinted polymers (MIPs) as extraordinary compounds with unique features have presented a wide range of applications and benefits to researchers. In particular when used as a sorbent in sample preparation methods for the analysis of biological samples and complex matrices. Its application in the extraction of medicinal species has attracted much attention and a growing interest. This review focus on articles and research that deals with the application of MIPs in the analysis of components such as biomarkers, drugs, hormones, blockers and inhibitors, especially in biological matrices. The studies based on MIP applications in bioanalysis and the deployment of MIPs in high-throughput settings and optimization of extraction methods are presented. A review of more than 200 articles and research works clearly shows that the superiority of MIP techniques lies in high accuracy, reproducibility, sensitivity, speed and cost effectiveness which make them suitable for clinical usage. Furthermore, this review present MIP-based extraction techniques and MIP-biosensors which are categorized on their classes based on common properties of target components. Extraction methods, studied sample matrices, target analytes, analytical techniques and their results for each study are described. Investigations indicate satisfactory results using MIP-based bioanalysis. According to the increasing number of studies on method development over the last decade, the use of MIPs in bioanalysis is growing and will further expand the scope of MIP applications for less studied samples and analytes.

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Tramadol sensing in non-invasive biological fluids using a voltammetric electronic tongue and an electrochemical sensor based on biomimetic recognition

Cited by 30 publications

References 75 publications

Validated analytical methods for estimation of tramadol

Validated analytical methods for estimation of tramadol

Graphene-Based Electrochemical Sensors for Psychoactive Drugs

Recent molecularly imprinted polymers applications in bioanalysis

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