Trajectory of Medication-Induced Constipation in Patients With Cancer

McMillan, Susan C.; Tofthagen, Cindy; Small, Brent J.; Karver, Sloan Beth; Craig, David W.

doi:10.1188/13.onf.e92-e100

Cited by 22 publications

(21 citation statements)

References 22 publications

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“…Patients were called on the telephone and asked about their constipation severity each week, as well as their use of laxatives, which may have increased their awareness of their symptoms in relation to laxative utilization. Interestingly, constipation severity scores increased near the end of the 5‐week study, which, the authors assert, may indicate that the effect of the telephone calls was “wearing off” . Similarly, several stool symptoms assessed by the PAC‐SYM in the current study, including too hard BM, incomplete BM, and straining/squeezing to pass BM, decreased and then trended upwards toward the end of the follow‐up period.…”

Section: Discussionsupporting

confidence: 51%

“…Scant longitudinal data on trajectories of OIC and laxative utilization and treatment response are available to contextualize these findings. McMillan et al (2013) sought to determine the severity and trajectory of constipation resulting from opioids and/or vinca alkaloids over an 8‐week longitudinal observational study of patients with cancer. The opioid group in that study exhibited a statistically significant decrease in constipation intensity across study visits, which the study authors point out may have partially resulted from the study design, despite the lack of intervention.…”

Section: Discussionmentioning

confidence: 99%

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Opioid-Induced Constipation Among Patients with Chronic Noncancer Pain in the United States, Canada, Germany, and the United Kingdom: Laxative Use, Response, and Symptom Burden Over Time

Coyne¹,

Margolis²,

Yeomans

et al. 2015

Pain Med

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Section: Discussionsupporting

confidence: 51%

Section: Discussionmentioning

confidence: 99%

Opioid-Induced Constipation Among Patients with Chronic Noncancer Pain in the United States, Canada, Germany, and the United Kingdom: Laxative Use, Response, and Symptom Burden Over Time

Coyne¹,

Margolis²,

Yeomans

et al. 2015

Pain Med

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“…Fatigue was the most common individual symptom explored -the focus of 18 of the manuscripts. Other individual symptoms included pain (e.g., Matthie & McMillan, 2014), constipation (McMillan, Tofthagen, Small, Karver, & Craig, 2013) and chronic cough (French, Crawford, Bova, & Irwin, 2017). Just over half of the investigators included more than one symptom, ranging from two or three symptoms to more than 30 symptoms (e.g., Almutary, Douglas, & Bonner, 2016).…”

Section: Symptomsmentioning

confidence: 99%

An integrative review of the theory of unpleasant symptoms

Blakeman

2019

Journal of Advanced Nursing

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Aims The aim of this study was to explore how the theory of unpleasant symptoms (TOUS) has been used in the methodological design and analysis of symptom research. Design An integrative review, using Whittemore and Knafl's approach. Data Sources Searches were conducted between 26 January–10 February 2018. Databases included CINAHL Complete, PubMed, Proquest Nursing and Allied Health Source, Health Source: Nursing/Academic Edition, Academic Search Complete and Google Scholar. Review Methods A systematic approach to searching, screening and analysing the literature was applied. The matrix method, content analysis, constant comparison, counting and clustering were used. Results Sixty‐four records were included. Most studies were quantitative, cross‐sectional, instrument‐based and conducted in the USA. Various symptoms and patient populations were represented and each of the TOUS concepts were explored. Conclusion Although the theory has a role to play in furthering symptom science, attention should be paid to the areas of the model and of symptom research that have received less attention. More complex statistical approaches and big data will help to illuminate symptom experiences. Additional focus on intervention studies and all symptom dimensions will help to advance symptom science research. Impact This review is the first to provide a comprehensive, systematic summary of the uses of the TOUS across the research literature to date. This theory is a diverse, holistic middle‐range theory capable of being applied to multiple symptoms and populations. Researchers should consider using the theory as a conceptual framework for studies to advance symptom science and explore symptoms holistically.

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“…It also founded in many disease condition; such as chronic illness and cancer [8]. Therefore, it is important to discuss how constipation affects the QOL and to understand the underlying causes of constipation.…”

Section: Introductionmentioning

confidence: 99%

“…The severity of constipation can fluctuate from minor to sever which may affect the individual's physical, psychological and social distress level [7]. Craig et al [8] identified the severity of constipation in patients with cancer by a descriptive cross-sectional study. The results showed that 63% of patients have constipation, mild to severe in intensity, caused symptom distress, and persisted over time.…”

Section: Introductionmentioning

confidence: 99%

Bowel Management: Constipation among Patients with Cancer

Younes¹,

Tawalbeh²

2017

J Palliat Care Med

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Constipation has a negative effect on patients with cancer and their families. It negatively affects the quality of life terms of physical, social, psychological, and spiritual dimensions. The aim of this paper was to review the studies that addressed constipation among patients with cancer and to explore its influence on the quality of life and wellbeing for patients and their families. Completed studies were identified through systematic search using Cumulative index for Nursing and Applied Health Literature, EBSCO Host, Ovid Journal and PubMed. This search located the studies that were published between 1989 and 2015 about constipation effect, pathophysiology, assessment and management. The review identified 44 studies and indicated that constipation has negative effect on QOL among patient with cancer and their families. Various assessment and management constipation tools and strategies were used according to patient's health condition. Pharmacological and non-pharmacological methodologies were used to manage constipation. Appropriate assessment has a positive impact on effective management of constipation among patients with cancer; that may help improve the quality of life. Nurses play a significant role in performing comprehensive assessment strategies to detect the risk factor for constipation and applying the prevention precaution to reduce opportunity of its occurrence. Nurses should perform constipation management strategies that include both pharmacological and non-pharmacological approaches.

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Trajectory of Medication-Induced Constipation in Patients With Cancer

Cited by 22 publications

References 22 publications

Opioid-Induced Constipation Among Patients with Chronic Noncancer Pain in the United States, Canada, Germany, and the United Kingdom: Laxative Use, Response, and Symptom Burden Over Time

Opioid-Induced Constipation Among Patients with Chronic Noncancer Pain in the United States, Canada, Germany, and the United Kingdom: Laxative Use, Response, and Symptom Burden Over Time

An integrative review of the theory of unpleasant symptoms

Bowel Management: Constipation among Patients with Cancer

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