Trajectories of life satisfaction after traumatic brain injury: Influence of life roles, age, cognitive disability, and depressive symptoms.

Abstract

Objectives 1) Identify life satisfaction trajectories after moderate to severe traumatic brain injury (TBI), 2) establish a predictive model for these trajectories across the first 5 years post-injury, and 3) describe differences in these life satisfaction trajectory groups, focusing on age, depressive symptoms, disability, and participation in specific life roles,. Research Method Analysis of the longitudinal TBI Model Systems National Database was performed on data collected prospectively at 1, 2, and 5 years post-TBI. Participants (n=3,012) had a moderate to severe TBI and were 16 years old and older. Results Four life satisfaction trajectories were identified across the first 5 years post-injury, including: Stable Satisfaction, Initial Satisfaction Declining, Initial Dissatisfaction Improving, and Stable Dissatisfaction. Age, depressive symptoms, cognitive disability, and life role participation as a worker, leisure participant, and/ or religious participant at one year post-injury significantly predicted trajectory group membership. Life role participation and depressive symptoms were strong predictors of life satisfaction trajectories across the first 5 years post TBI. Conclusions The previously documented loss of life roles and prevalence of depression after a moderate to severe TBI make this a vulnerable population for whom low or declining life satisfaction is a particularly high risk. Examining individual life role participation may help to identify relevant foci for community-based rehabilitation interventions or supports.

Clostridium butyricum exerts a neuroprotective effect in a mouse model of traumatic brain injury via the gut‐brain axis

“…Our experiment used a mouse model in which TBI was induced with the weight-drop method, which frequently resulted in cortical contusion and a series of neurological impairments. 39 In our previous studies, Cb treatment was shown to potentially attenuate cognitive disorder in mice. [40][41][42] Consistent with our present study, Cb treatment significantly ameliorated TBI-induced neurological deficits.…”

“…Neurological deficits are often the cause of disability after TBI. Our experiment used a mouse model in which TBI was induced with the weight‐drop method, which frequently resulted in cortical contusion and a series of neurological impairments . In our previous studies, Cb treatment was shown to potentially attenuate cognitive disorder in mice .…”

A narrative literature review of depression following traumatic brain injury: prevalence, impact, and management challenges

“…Other predictors of PTD are discussed in the “Predictors/etiology of depression” section. Finally, PTD up to and beyond 10 years post-injury was associated with lower and declining life satisfaction40–42 and with poorer quality of life after TBI 3,25,43–45. A study by Diaz et al45 reported that those with depression after TBI had greater impairments in all domains of the Short Form Health Survey (SF-36), a health-related quality of life measure, compared to those without depression.…”

Community Participation for People with Trauma Injuries: A Study Protocol of a Crossover Randomised Controlled Trial of the Effectiveness of a Community Mobility Group Intervention (CarFreeMe TI)

“…Research demonstrates that life roles, such as being a driver, are important for life satisfaction after injuries, such as TBI and SCI (Juengst et al, 2015). Future studies need to examine participation in life roles; moreover, the personal importance and changes in these specific life roles (for example, driving and community mobility) after trauma injuries.…”