Training-induced changes of motor cortex representations in stroke patients

Liepert, Joachim; Graef, S.; Uhde, Ina; Leidner, Ottmar; Weiller, Cornelius

doi:10.1034/j.1600-0404.2000.90337a.x

Cited by 174 publications

(129 citation statements)

References 18 publications

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“…Changes include shrinkage of the cortical representation synonymous with the area of injury (Toldi et al 1996), the corresponding area in the uninjured cortex and invasion of adjacent territory by neighbouring representations (Nudo et al 1997). This motor cortical reorganisation can be influenced by training tasks and studies have shown that functional recovery mirrors further cortical reorganisation (Nudo et al 1996, Liepert et al 2000, Schmidlin et al 2004). …”

Section: Introductionmentioning

confidence: 99%

Mapping the cortical representation of the lumbar paravertebral muscles

O’Connell

Maskill

Cossar

et al. 2007

Clinical Neurophysiology

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ObjectiveThe aim of this study was to map the cortical representation of the lumbar spine paravertebral (LP) muscles in healthy subjects. MethodsTranscranial magnetic stimulation (TMS) was employed to map the cortical representations of the LP muscles at 2 sites. Stimuli were applied to points on a grid representing scalp positions. The amplitude of motor evoked potentials (n=6) were averaged for each position. ResultsThe optimal site for evoking responses in the contralateral LP muscles was situated 1cm anterior and 4 cm lateral to the vertex. Ipsilateral responses were evoked from sites lateral to the optimal site for evoking contralateral responses. Contralateral responses were also obtained from areas anterior to the optimal site. ConclusionsMaps of these muscles can be produced. The results suggest discrete contra and ipsilateral cortical projections. Anterior sites at which excitation can be evoked may indicate projections arising in the SMA are involved. SignificanceThis study provides normative data regarding the cortical representation of the paravertebral muscles and provides a technique for evaluating cortical motor plasticity in patients presenting with spinal pathologies.

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Section: Introductionmentioning

confidence: 99%

Mapping the cortical representation of the lumbar paravertebral muscles

O’Connell

Maskill

Cossar

et al. 2007

Clinical Neurophysiology

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“…This change required 15 to 30 minutes of continuous effort of one movement and extinguished after approximately 20 to 30 minutes. After stroke, increased amounts of task repetition have been shown to cause cortical changes and functional improvement [6][7][8]. As a specific example, in Carey et al, subjects with impaired grasp-and-release secondary to stroke performed more than 100 reps per day (1,200 total) of a finger-tracking exercise and demonstrated significant cortical reorganization and functional improvement compared with control subjects [6].…”

Section: Introductionmentioning

confidence: 99%

Comparison of amounts and types of practice during rehabilitation for traumatic brain injury and stroke

Kimberley¹,

Samargia²,

Moore³

et al. 2010

JRRD

118

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Abstract-Patients with acquired neurological deficits may capitalize on cortical reorganization to recover functional skills that have been lost. Research in neuroplasticity proposes that a high number of repetitions may lead to cortical reorganization. The purposes of this study were to quantify the number and type of activities performed by patients with traumatic brain injury (TBI) and stroke in physical and occupational therapy sessions to determine whether (1) the number of repetitions approaches the numbers in neuroplasticity research, (2) there were differences based on patient diagnosis, and (3) patient or therapist characteristics affected the type or amount of activities performed. Forty-eight patient and forty provider subjects participated. One hundred seven therapy sessions were observed. Data from therapy sessions were counted and categorized. Neither patient group approached the total number of repetitions neuroplasticity research suggests may be required for neuroplastic change. Repetitions per session did not differ between groups. Subjects with TBI performed more repetitions per minute in three categories (total upper-limb repetitions, gait steps, and transfers) than subjects with stroke. Therapists with <1 year or >15 years of neurological therapy experience instructed patients in fewer functional repetitions per minute than did therapists with 5 to 15 years of experience.

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“…Liepert et al [43] examined the effects on dexterity and motor cortex function of a single task-oriented session focussed on improving dexterity of mildly to moderately paretic hand in patients early (4-8 weeks) after stroke. They observed that the size of the representation in contra-lateral motor cortex of paretic hand enlarged whereas that of the unaffected hand was unchanged.…”

Section: Discussionmentioning

confidence: 99%

A Comparison between Task Oriented and Client-Centred Task-Oriented Approaches to Improve Upper Limb Functioning in People with Sub-Acute Stroke

2015

J Nov Physiother

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Training-induced changes of motor cortex representations in stroke patients

Abstract: A single session of physiotherapy produces a use-dependent enlargement of motor cortex representations paralleled by an improvement of motor function in stroke patients.

Cited by 174 publications

References 18 publications

Mapping the cortical representation of the lumbar paravertebral muscles

Mapping the cortical representation of the lumbar paravertebral muscles

Comparison of amounts and types of practice during rehabilitation for traumatic brain injury and stroke

A Comparison between Task Oriented and Client-Centred Task-Oriented Approaches to Improve Upper Limb Functioning in People with Sub-Acute Stroke

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