Traditional uses, phytochemistry, pharmacology, and toxicology of Coreopsis tinctoria Nutt.: A review

Shen, Jie; Hu, Mengyin; Wei, Tan; Ding, Jiwei; Jiang, Baoping; Xu, Lei; Hasimu, Hamulati; He, Chunnian; Sun, Ying; Xiao, Pei‐Gen

doi:10.1016/j.jep.2020.113690

Cited by 37 publications

(26 citation statements)

References 64 publications

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“…It could be affected by monosaccharide composition, molecular weight, branched chain structure, high-level structure, etc. Existing studies have found that the mechanisms of polysaccharides for hypoglycemic activity mainly include regulation of enzyme activity, liver glucose metabolism, intestinal flora, protection and reparation of pancreatic islet cells, and improvement of insulin sensitivity [ 105 , 106 , 107 , 108 , 109 ].…”

Section: Biological Activitymentioning

confidence: 99%

Recent Developments in Inonotus obliquus (Chaga mushroom) Polysaccharides: Isolation, Structural Characteristics, Biological Activities and Application

Jia

Xue

et al. 2021

Polymers

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Inonotus obliquus (Chaga mushroom) is a kind of medicine and health food widely used by folk in China, Russia, Korea, and some occidental countries. Among the extracts from Inonotus obliquus, Inonotus obliquus polysaccharide (IOPS) is supposed to be one of the major bioactive components in Inonotus obliquus, which possesses antitumor, antioxidant, anti-virus, hypoglycemic, and hypolipidemic activities. In this review, the current advancements on extraction, purification, structural characteristics, and biological activities of IOPS were summarized. This review can provide significant insight into the IOPS bioactivities as their in vitro and in vivo data were summarized, and some possible mechanisms were listed. Furthermore, applications of IOPS were reviewed and discussed; IOPS might be a potential candidate for the treatment of cancers and type 2 diabetes. Besides, new perspectives for the future work of IOPS were also proposed.

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Section: Biological Activitymentioning

confidence: 99%

Recent Developments in Inonotus obliquus (Chaga mushroom) Polysaccharides: Isolation, Structural Characteristics, Biological Activities and Application

Jia

Xue

et al. 2021

Polymers

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“…tinctoria (known as snow chrysanthemum) and C . lanceolata [ 3 , 5 , 6 , 12 , 26 , 27 , 28 , 29 ]. Moreover, its mass spectrum was compared to that in Waters Traditional Medicine Library that is built in UNIFI software (Waters, Milford, MA, USA) and MassBank available online (a public database for sharing mass spectral data) [ 30 , 31 ].…”

Section: Resultsmentioning

confidence: 99%

“…Thus, peak 14 was tentatively identified as 7,3′,5′-trihydroxyflavanone- O -diglucoside. Given that 7,3′,5′-trihydroxyflavanone-7- O -glucoside and its aglycone have been found in Coreopsis species [ 3 , 28 ], three types of this compound, 7,3′,5′-trihydroxyflavanone-7- O -(glucosyl glucoside), 7,3′,5′-trihydroxyflavanone-7,3′- O -di glucoside, and 7,3′,5′-trihydroxyflavanone-7,5′- O -diglucoside were predicted as possible structures; however, the three compounds have not been described previously. Peak 18 ( t R 6.91 min) produced a molecular ion at m/z 581.1501 [M – H] − (calculated for C 26 H 29 O 15 − , 581.1512) and the fragment ion at m/z 287.0552 [M – H – arabinose – glucose] by a loss of the arabinosyl-glucose.…”

Section: Resultsmentioning

confidence: 99%

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Metabolite Profiling and Dipeptidyl Peptidase IV Inhibitory Activity of Coreopsis Cultivars in Different Mutations

Kim

Paudel

Han

et al. 2021

Plants

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Coreopsis species have been developed to produce cultivars of various floral colors and sizes and are also used in traditional medicine. To identify and evaluate mutant cultivars of C. rosea and C. verticillata, their phytochemical profiles were systematically characterized using ultra-performance liquid chromatography time-of-flight mass spectrometry, and their anti-diabetic effects were evaluated using the dipeptidyl peptidase (DPP)-IV inhibitor screening assay. Forty compounds were tentatively identified. This study is the first to provide comprehensive chemical information on the anti-diabetic effect of C. rosea and C. verticillata. All 32 methanol extracts of Coreopsis cultivars inhibited DPP-IV activity in a concentration-dependent manner (IC50 values: 34.01–158.83 μg/mL). Thirteen compounds presented as potential markers for distinction among the 32 Coreopsis cultivars via principal component analysis and orthogonal partial least squares discriminant analysis. Therefore, these bio-chemometric models can be useful in distinguishing cultivars as potential dietary supplements for functional plants.

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“…Therefore, it is uncertain if vaccinated individuals could be a source of infection, even for a restricted time and with a reduced viral load. Furthermore, the appearance of new virus variants in addition to D614G and B.1.1.7, which appear less susceptible to vaccines in the laboratory [ [9]], is a cause of concern.…”

Section: Endoscopy During the Covid-19 Pandemic: Is It Time To Down-grade Personal Protective Equipment For Vaccinated Personnel?mentioning

confidence: 99%

Endoscopy during the COVID-19 pandemic: Is it time to down-grade personal protective equipment for vaccinated personnel?

Elli

Rimondi

Tontini

et al. 2021

Digestive and Liver Disease

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Traditional uses, phytochemistry, pharmacology, and toxicology of Coreopsis tinctoria Nutt.: A review

Cited by 37 publications

References 64 publications

Recent Developments in Inonotus obliquus (Chaga mushroom) Polysaccharides: Isolation, Structural Characteristics, Biological Activities and Application

Recent Developments in Inonotus obliquus (Chaga mushroom) Polysaccharides: Isolation, Structural Characteristics, Biological Activities and Application

Metabolite Profiling and Dipeptidyl Peptidase IV Inhibitory Activity of Coreopsis Cultivars in Different Mutations

Endoscopy during the COVID-19 pandemic: Is it time to down-grade personal protective equipment for vaccinated personnel?

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