Traditional Uses of Medicinal Plants of Summer Hill, Shimla

Pracheta, Pracheta

doi:10.20959/wjpps20179-9708

Cited by 1 publication

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References 7 publications

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“…Pracheeta et al stated that flavonoids inhibit bacterial growth by damaging cell walls and cytoplasmic membranes. The ability of saponins to act as an antibacterial compound is because they cause leakage of proteins and enzymes from within the cell [54]. Similarly, Wiyanto [55] stated that steroids could inhibit microbes by damaging the plasma membrane and causing the release of the cytoplasm due to leakage, leading to cell death [55].…”

Section: Inhibitory Area Width (Iaw) Test Resultsmentioning

confidence: 99%

Bioactivities and Chemical Compositions of Cinnamomum burmannii Bark Extracts (Lauraceae)

et al. 2023

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Cinnamomum burmanni has antifungal and antibacterial properties, including alkaloids, tannins, flavonoids, saponins, terpenoids, and essential oil content of cinnamaldehyde, eugenol, and safrole. This study aims to determine the antibacterial properties against Streptococcus mutans and Staphylococcus aureus, antifungal properties against Candida albicans and Candida tropicalis, antioxidant, and flavonoid content of microwave-assisted extraction (MAE) extracts from C. burmanni bark. This study began with the MAE extraction of C. burmanni, followed by qualitative phytochemical tests on the alkaloids, tannins, flavonoids, saponins, and terpenoid groups. Furthermore, using the UV-Vis spectrophotometry method, a quantitative phytochemical test was performed to determine the levels of flavonoids. The 1,1-diphenyl-2-pikrilhidrazil (DPPH) method was used for the antioxidant test, the agar dilution method for the minimum inhibitory concentration (MIC), and the paper disc diffusion method for the width of the inhibitory area (LDH). The positive antifungal control was nystatin, while the antibacterial control was amoxicillin, and both negative controls were 1% dimethyl sulfoxide (DMSO). The antifungal and antibacterial components were found to be 3% n-hexane extract from the bark of C. burmanni, with an inhibitory area width (IAW) of 13.83 mm. The best antioxidant results were the ethanol extract with a very active category IC50 of 8.533 ppm, 5.90%, and the highest ethanol extract containing flavonoid test results.

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Section: Inhibitory Area Width (Iaw) Test Resultsmentioning

confidence: 99%