2021
DOI: 10.1155/2021/5674142
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Traditional East Asian Herbal Medicine for Amyotrophic Lateral Sclerosis: A Scoping Review

Abstract: This study aimed to analyze and summarize the existing evidence regarding herbal medicine treatments for amyotrophic lateral sclerosis (ALS). Studies on herbal medicine treatment in patients with ALS were searched within English, Chinese, Japanese, and Korean databases up to July 31, 2021. In the selected studies, we collected the following information: the first author, year of publication, country, language, study methodology, sample size, demographic characteristics of the study participants, disease durati… Show more

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Cited by 6 publications
(10 citation statements)
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“…One good study I was able to find [36] examined and summarized 59 studies that focused on the effect of herbal medicine on the treatment of ALS. Most of those studies were conducted in China; some were conducted in Korea.…”
Section: Traditional Chinese Medicinementioning
confidence: 99%
“…One good study I was able to find [36] examined and summarized 59 studies that focused on the effect of herbal medicine on the treatment of ALS. Most of those studies were conducted in China; some were conducted in Korea.…”
Section: Traditional Chinese Medicinementioning
confidence: 99%
“…The cause of ALS has yet to be elucidated; however, ∼5-10% of patients with ALS are thought to suffer from a familial form of ALS that exerts familial genetic characteristics and feature mutations in several genes including C9orf72, SOD1, FUS, and TARDBP. The remaining 90% of patients are considered as sporadic cases of ALS associated with abnormalities of the immune system, toxic exposure, mitochondrial dysfunction, oxidative stress, neuroinflammation, or glutamate poisoning (2)(3)(4)(5).…”
Section: Introductionmentioning
confidence: 99%
“…This condition progresses rapidly, and the median survival duration is around 3–5 years from primary symptoms to death ( 3 ). This disease has an incidence of 2.5 per 100,000 persons-years and is more prevalent in men than in women ( 4 ). The cause of ALS has yet to be elucidated; however, ~5–10% of patients with ALS are thought to suffer from a familial form of ALS that exerts familial genetic characteristics and feature mutations in several genes including C9orf72, SOD1, FUS , and TARDBP .…”
Section: Introductionmentioning
confidence: 99%
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