Traditional Chinese Medicine for Sexual Dysfunction: Review of the Evidence

Chubak, Barbara; Doctor, Alaethia

doi:10.1016/j.sxmr.2017.11.007

Cited by 11 publications

(7 citation statements)

References 18 publications

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“…Our review is the first to systematically approach research into the FSD treatments. Two narrative reviews have provided updates on pharmacological treatments [23] and Chinese herbal medicine [24] and conducted a meta-analysis to assess the placebo effect of interventions for female sexual desire [5]. In our systematic review, we also included a study to assess the effectiveness of DIFSD treatment.…”

Section: What Is New About Other Similar Reviews?mentioning

confidence: 99%

The Use of Natural Products for the Treatment of Female Sexual Dysfunction: A Systematic Review of Randomized Clinical Trials

Jurado¹,

Jouda-Benazouz²,

Mendoza-Huertas³

et al. 2020

ASM

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Female sexual dysfunction (FSD) affects 40% of the world's females, most of which are disorders linked to desire or interest/excitement. Whilst all types of therapy that attempt to improve female sexual desire have long been established, the results are contradictory. Objective: To analyze all available evidence to validate the effectiveness of natural therapies in the treatment of FSD. Method: The study was registered at http://www.prospero.org (CRD42019127700). We searched the Institute for Scientific Information Web of Knowledge, MEDLINE, Pubmed, Scopus and Cochrane databases for all articles published in peerreviewed journals in April 2019 (in any language). The PICOS standard is women with FSD; (intervention) of any type of Natural therapy; (outcome) primary outcome: frequency of changes, severity, and average mean scores on sexual symptoms measured with a validated instrument, secondary outcome: quality of life; (study design) and randomized clinical trial (RCT). Results: The literature search strategy identified 95 articles, 81 of which were excluded at the different search stages. Finally, we systematically reviewed 15 RCTs, 11 of which referred to primary FSD, and four of which analyzed women with drug-induced FSD (DFSD). Most of them analyzed hypoactive sexual desire disorder. Although differences related to placebo were found in most people, the majority of the studies are considered to be of poor quality and low external effectiveness. Conclusion: Although the quality of the evidence is not high, most natural product interventions appear to improve FSD, particularly hypoactive sexual desire disorders including those categorized as primary and drug-induced.

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Section: What Is New About Other Similar Reviews?mentioning

confidence: 99%

The Use of Natural Products for the Treatment of Female Sexual Dysfunction: A Systematic Review of Randomized Clinical Trials

Jurado¹,

Jouda-Benazouz²,

Mendoza-Huertas³

et al. 2020

ASM

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“…Acupuncture is a key component of traditional Chinese medicine (TCM) as it attaches immense importance to the integration of this concept. Acupuncture has been used quite frequently for treating various urologic disorders, including both male and female sexual dysfunctions [ 14 , 15 ], with a majority of the research focusing on ED [ 16 ]. Many systematic reviews have analyzed the current evidence on ED treatment to prove or discuss their effects [ 17 ].…”

Section: Introductionmentioning

confidence: 99%

The Efficacy of Acupuncture on Patients with Erectile Dysfunction: A Review

Guo

Wang

2022

Evidence-Based Complementary and Alternative Medicine

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Erectile dysfunction (ED) is one of the most common sexual dysfunctions in men. The prevalence of ED has been increasing in recent years, which has critically affected male reproductive health and quality of life. According to various guidelines, phosphodiesterase-5 inhibitors are the most commonly recommended drugs for treating ED. However, many patients turn to alternative therapies because of adverse reactions, such as headache, and the poor efficacy of these drugs. Acupuncture is a long-established treatment in traditional Chinese medicine (TCM) and has been approved by the World Health Organization for improving penile erection as well as other discomforts in patients. However, previous systematic reviews have not discussed the characteristics and the related mechanisms of acupuncture treatment. Therefore, this study focuses on summarizing the characteristics and advantages of TCM in acupuncture treatment for ED based on relevant literature and on predicting and analyzing the related mechanisms.

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“… 2019 ). Based on these factors, traditional Chinese medicine (TCM) has attracted the attention of researchers as it is a natural form of medicine with fewer side effects, and can be made up of easily available properties (Chubak and Doctor 2018 ).…”

Section: Introductionmentioning

confidence: 99%

“…TCM has been used widely to treat sexual dysfunction in China for more than 2000 years, which significantly improves the sexual function of patients with sexual dysfunction (Chubak and Doctor 2018 ). TCM believes that the onset of sexual dysfunction is related to the imbalance of Yin-Yang in the kidney and liver, and is combined with Qi-deficiency and blood-stasis (Wei and Wei 2019 ).…”

Section: Introductionmentioning

confidence: 99%

Efficacy of Yougui pill combined with Buzhong Yiqi decoction in alleviating the sexual dysfunction in female rats through modulation of the gut microbiota

Wang

Shi

et al. 2021

Pharmaceutical Biology

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Context Yougui pill combined with Buzhong Yiqi decoction (YPBYD) is used to relieve sexual dysfunction in clinical practice. Objective To investigate changes in microbial composition caused by sexual dysfunction and identify dominant bacteria related to YPBYD treatment. Materials and methods Female Sprague-Dawley rats were randomly divided into four groups ( n = 6): one group underwent Sham operation (Sham group), while three groups underwent ovariectomy (one model and two treatment groups). The ovariectomized (OVX) rats received oestradiol benzoate (250 µg/kg/week) or YPBYD (3.6 mL/d) via oral gavage for 4 weeks. Vaginal smear assay was performed; the serum levels of cyclic adenosine monophosphate (cAMP) and oestradiol (E2) were measured, followed by collection of stool samples for 16S rRNA sequencing. Results After YPBYD treatment, the levels of E2 and cAMP in OVX rats significantly increased (E2: from 20.45 ± 1.60 ng/L to 24.38 ± 1.70 ng/L; cAMP: from 261.41 ± 9.21 pg/mL to 373.75 ± 17.37 pg/mL). OVX treatment decreased diversity of gut microbiota and YPBYD treatment restored gut microbiota composition. Compared with Sham group, the abundance of Romboutsia significantly increased, while those of Proteobacteria and Staphylococcus markedly decreased in OVX group (all p < 0.05); meanwhile, the abundance of these microbes showed an opposite trend after YPBYD treatment. These microbiotas were involved in tyrosine and tryptophan biosynthesis and fatty acid metabolism. Discussion and conclusions These findings are the first to indicate YPBYD can alleviate female sexual dysfunction by modulating gut microbiota in OVX rats, which will help enhance the understanding on potential mechanism of YPBYD against sexual dysfunction.

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Traditional Chinese Medicine for Sexual Dysfunction: Review of the Evidence

Cited by 11 publications

References 18 publications

The Use of Natural Products for the Treatment of Female Sexual Dysfunction: A Systematic Review of Randomized Clinical Trials

The Use of Natural Products for the Treatment of Female Sexual Dysfunction: A Systematic Review of Randomized Clinical Trials

The Efficacy of Acupuncture on Patients with Erectile Dysfunction: A Review

Efficacy of Yougui pill combined with Buzhong Yiqi decoction in alleviating the sexual dysfunction in female rats through modulation of the gut microbiota

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