Traditional and Ethnobotanical uses Premna barbata Wall. Ex Schauer in Kumaun and Garhwal Regions of Uttarakhand, India and Other Western Himalayan Countries- A Review

Abstract

The Himalayas are a repository of tremendous wealth of medicinal plants. Kumaun and Garhwal are characterized by a rich diversity of ethno-medicinal plants as well as a rich heritage site in traditional medicine system in the western Himalayan region. Present study deals with the status, identification and to explore the traditional knowledge of plant Premna Barbata Wall. Ex Schauer about its uses in local medicine by village people in Kumaun, Garhwal region in India and other western Himalayan Countries. The genus Premna contains 200 species under the family Verbenaceae all over the world and out of that approximately 30 species are present in India and are native mainly to the tropical and subtropical Asia, Africa, Australia and the Pacific islands. Premna Barbata Wall. Ex Schauer plant is belonging to family Verbenaceae. It is distributed in the forest area of the Eastern and northern parts of India, Pakistan, Nepal, and Myanmar and nearby regions.The present paper is a review on ethno-medicinal uses of Premna Barbata Wall. Ex Schauer, which is widely used by different tribes and medicinal practitioners for treatment of various diseases. Different parts of the plant (bark, wood and leaves) are variably used in treating wide range of diseases such as joints and back pain, dropsy, ulcer, diarrhea, wound healing, throat infection, antibacterial, fever, herpes complex disease, arthritic pain. With this review it is concluded that there is a need for conducting further investigation and studies for pharmacognostic characteristics and the isolation of individual active constituents form Premna Barbata Wall. Ex Schauer plant. Also the study is expected to provide basic data for further studies aimed at conservation of traditional medicine.

In Vitro Antiproliferative Efficacy, Antioxidant Activity and LC MS Based Metabolite Profiling of Premna Barbata Stem Bark

“…It has been reported to possess glycoside, iridoid glycoside, alkaloid, flavonoid, terpenoids, volatile oil, polysaccharide and fatty acids. 3,4,5 A new iridoid glycoside Premnosidic acid was first compound from the bark of the plant reported by Negi et al 4 Earlier in some studies reports suggests that Premnosidic acid possesses the free radical scavenging and antioxidant activities. 6 Antibacterial activity has also been reported by the plant previously.…”