Traditional and complementary treatments do have a role to play in global health, but probably not in emerging pandemics

Wardle, Jon

doi:10.1016/j.aimed.2020.02.003

Cited by 6 publications

(4 citation statements)

References 22 publications

(18 reference statements)

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“…16,46 High fever, bleeding, and blood vessel damage are all symptoms of dengue fever. 47 The Lassa virus is to blame for Lassa fever, which is characterized by a high fever, bleeding, and blood vessel damage. 1 The Rift Valley fever virus is the cause of this illness, which is characterized by a high fever, bleeding, and blood vessel damage.…”

Section: Pathogen-mediated Damagementioning

confidence: 99%

“…Neurological side effects such as confusion, seizures, or other symptoms are possible in certain patients. 47 The disease can occasionally be transmitted from person to person, which could cause epidemics. If someone encounters the signs of hemorrhagic fever, they must consult a doctor right away since timely care can improve results while reducing the risk of major health problems.…”

Section: Outcomes Of Pathogen-induced Hemorrhagic Fevermentioning

confidence: 99%

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The Role of Endothelial Cell Dysfunction in Hemorrhagic Fevers

Ghazaei

2023

Int J Basic Sci Med

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Endothelial cells (ECs) that line the inner surface of blood vessels play a crucial role in maintaining healthy blood vessels and regulating consistent blood flow. EC dysfunction (ECD) is the improper functioning of ECs as a result of any modification or damage. Numerous health issues such as cardiovascular disease, hypertension, lightheadedness, exhaustion, diabetes, and the like could result from this. Both extrinsic and intrinsic factors may cause ECD. Many virus-induced hemorrhagic fevers, including dengue fever, Ebola, and Lassa fever, exhibit ECD. ECs maintain barrier functions by regulating immune cell interactions, homeostasis, and capillary permeability, and in viral infections, viral interaction alters these factors. These pathogens destroy ECs, leading to a loss of integrity in the blood vessels and increased permeability. Hemorrhagic fever can cause a wide range of symptoms such as fever, headache, muscle pain, weakness, exhaustion, bruises, bleeding, shock, and occasionally even the emergence of additional issues such as organ failure. Hemorrhagic fevers can be life-threatening if not treated promptly and correctly. Considering that ECD can be a silent condition, consultation with physicians about individuals’ risk factors and regular screenings to detect and prevent this condition is highly important. There is no specific antiviral treatment for most hemorrhagic fevers, but research is ongoing to develop effective treatments. This review will discuss the ECD due to viral interactions to cause hemorrhagic fevers, available treatments, and challenges associated with such viral hemorrhagic fevers (VHFs).

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Section: Pathogen-mediated Damagementioning

confidence: 99%

Section: Outcomes Of Pathogen-induced Hemorrhagic Fevermentioning

confidence: 99%

The Role of Endothelial Cell Dysfunction in Hemorrhagic Fevers

Ghazaei

2023

Int J Basic Sci Med

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“…But we also highlighted that TCIM may not be the only answer in addressing public health scenarios such as a pandemic [15] , and that traditional and complementary health approaches were not the only tools that should be considered by integrative health professionals during COVID-19 [16] . And the ‘other’ part of integrative health that makes up the ‘best of both worlds’ – biomedical interventions – has had some remarkable successes (though admittedly some failures too) in this pandemic.…”

mentioning

confidence: 99%

Integrative health needs to engage with effective public health interventions on merit, not oppose them on them on principle

Wardle

2021

Advances in Integrative Medicine

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“…The editorial published at the outset of the COVID-19 outbreak – in which integrative medicine clinicians were cautioned about the role of integrative medicine in the pandemic [ 1 ] – has led to several inquiries from clinicians over the past few months. Many have questioned why an integrative medicine journal would suggest that integrative medicine should not be considered part of the toolbox in the global pandemic response.…”

mentioning

confidence: 99%

Maslow’s hammer in integrative medicine: one size will never fit all

2020

Advances in Integrative Medicine

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Traditional and complementary treatments do have a role to play in global health, but probably not in emerging pandemics

Cited by 6 publications

References 22 publications

The Role of Endothelial Cell Dysfunction in Hemorrhagic Fevers

The Role of Endothelial Cell Dysfunction in Hemorrhagic Fevers

Integrative health needs to engage with effective public health interventions on merit, not oppose them on them on principle

Maslow’s hammer in integrative medicine: one size will never fit all

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