Tracking the Violent Criminal Offender through DNA Typing Profiles — a National Database System Concept

Baechtel, F. Samuel; Monson, Keith L.; Forsen, G. E.; Budowle, Bruce; Kearney, James

doi:10.1007/978-3-0348-7312-3_26

Cited by 15 publications

(9 citation statements)

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“…The DNA was then whole-genome ampliWed using a GenomiPhi kit (Amersham), and the resulting reactions were subsequently used as templates in the PCR ampliWcation of polymorphic simple tandem repeat (STR) markers. STRs were selected primarily from the Weber v10 screening set, beginning with those that comprise the Combined DNA Index System (CODIS) set (Baechtel et al 1991). STR markers were resolved on an ABI 3730 capillary sequencer and analyzed using Genemapper v3.5 software (Applied Biosystems).…”

Section: Zygosity Determinationmentioning

confidence: 99%

A twin study of auditory processing indicates that dichotic listening ability is a strongly heritable trait

Morell

Brewer

et al. 2007

Hum Genet

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We administered tests commonly used in the diagnosis of auditory processing disorders (APDs) to twins recruited from the general population. We observed significant correlations in test scores between co-twins. Our analyses of test score correlations among 106 MZ and 33 DZ twin pairs indicate that dichotic listening ability is a highly heritable trait. Dichotic listening is the ability to identify and distinguish different stimuli presented simultaneously to each ear. Deficits in dichotic listening skills indicate a lesion or defect in interhemispheric information processing. Such defects or lesions can be prominent in elderly listeners, language-impaired children, stroke victims, and individuals with PAX6 mutations. Our data indicates that other auditory processing abilities are influenced by shared environment. These findings should help illuminate the etiology of APDs, and help to clarify the relationships between auditory processing abilities and learning/language disorders associated with APDs.

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Section: Zygosity Determinationmentioning

confidence: 99%

A twin study of auditory processing indicates that dichotic listening ability is a strongly heritable trait

Morell

Brewer

et al. 2007

Hum Genet

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“…Because seven out of nine loci from the present study are located on the same chromosomes as the loci from the CODIS set [3] purposes such as D2S1338, analysis of linkage disequilibrium (LD) was performed to assess the deviations from independence. The analysis was based on a subset of 302 samples, which were additionally fully typed for the loci included in the PowerPlex 16 (Promega) and SEfiler (Applied Biosystems) kits.…”

mentioning

confidence: 99%

Validation of nine non-CODIS STR loci for forensic use in a population from Central Poland

Kuźniar

Jastrzebska

Płoski

2006

Forensic Science International

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“…Fluorescent multiplex PCR was used according to the manufacturer's recommendations to amplify 15 tetranucleotide-repeat microsatellite loci contained in the commercially available AmpFlSTR Identifiler PCR Amplification Kit (Applied Biosystems) ( Table 1). The research panel includes 13 STRs that constitute the STR standardization project -CODIS announced in 1997 by the FBI and adopted afterward by forensic DNA analysts worldwide [7]. Genotyping was performed in a 310 ABI Prism Genetic Analyzer (Applied Biosystems) using GeneScan v3.7 and Genotyper v3.7 software.…”

Section: Methodsmentioning

confidence: 99%

Loss of heterozygosity (LOH)--implications for human genetic identification.

Pepiński

Sołtyszewski²,

Skawrońska³

et al. 2009

Folia Histochem Cytobiol.

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Abstract:The aim of this study was assessment of possible effects of loss of heterozygosity on human genetic identification of histolopathogical tissue sections. DNA templates were extracted from tumour tissue specimens excised from oncological patients and from reference blood samples. AmpFlSTR Identifiler PCR Amplification Kit and ABI 310 Genetic Analyzer (Applera) were used to obtain genetic profiles. Frequency of LOH was calculated for respective samples. Fisher's exact test was performed for statistical analysis. Forty-two percent of the 101 cancer cases analysed were found to possess alterations of the microsatellites manifesting with allelic loss. The most frequently altered loci were D3S1358 and D18S51. The alteration was detected in 47% of cases with larynx carcinoma, 44% of cases with uveal melanoma, 60% of cases with cervical cancers, one case of liposarcoma G3 and one case od neurofibrosarcoma. No LOH was found in liposarcoma G1, dermatofibrosarcoma and cystosarcoma protuberans in either primary or recurrent tumours. In benign tumours (lipoma and fibroma) LOH was also absent. During genotyping of DNA extracted from histopathological tissue sections caution should be taken when non-match or exclusion based on few discrepancies is concluded.

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Tracking the Violent Criminal Offender through DNA Typing Profiles — a National Database System Concept

Cited by 15 publications

References 0 publications

A twin study of auditory processing indicates that dichotic listening ability is a strongly heritable trait

A twin study of auditory processing indicates that dichotic listening ability is a strongly heritable trait

Validation of nine non-CODIS STR loci for forensic use in a population from Central Poland

Loss of heterozygosity (LOH)--implications for human genetic identification.

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