Tracheobronchopathia Osteochondroplastica

LESKE, VIVIAN; Lazor, Romain; Coëtmeur, D.; Crestani, Bruno; Chatté, G.; Cordier, Jean-François

doi:10.1097/00005792-200111000-00004

Cited by 128 publications

(189 citation statements)

References 70 publications

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“…[1][2][3] Wheezing was noted in 32% of the human patients in one study. 1 Difficult endotracheal intubations have been encountered infrequently in individuals with TO. 1,4,5 The diagnosis of TO is readily established with bronchoscopy and histologic examination of nodules.…”

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confidence: 93%

“…Many affected people are asymptomatic, and TO frequently is detected coincidentally during examination for other respiratory or nonrespiratory diseases or at autopsy. 1,2 Although TO in many people is clinically silent, some individuals show clinical signs referable to the disease. The most commonly reported clinical signs directly attributable to TO are cough, dyspnea with exertion, hemoptysis, recurrent infections, and lung lobe collapse secondary to airway obstruction.…”

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confidence: 99%

“…1 Difficult endotracheal intubations have been encountered infrequently in individuals with TO. 1,4,5 The diagnosis of TO is readily established with bronchoscopy and histologic examination of nodules. Endoscopically, TO is characterized by fixed, bony or cartilaginous nodules protruding into the tracheal lumen.…”

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confidence: 99%

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Tracheobronchopathia Osteochondroplastica in a Dog

et al. 2004

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A 9-year-old spayed female West Highland White Terrier was referred to the Washington State University (Pullman, WA) Veterinary Teaching Hospital (WSU-VTH) for evaluation of a suspected tracheal mass. For most of her life, the dog had experienced periodic respiratory difficulty, primarily inspiratory, after exercise. An increased frequency of episodes of respiratory difficulty was reported in the 6 months before examination at the WSU-VTH. Neither coughing nor other clinical signs suggestive of respiratory disease were observed between episodes of respiratory difficulty. Thoracic radiographs obtained by the referring veterinarian approximately 6 months before examination at the WSU-VTH were consistent with focal tracheal thickening.Additional history offered no clues to the origin of the dog's respiratory signs. The dog had been obtained as a puppy from Missouri and had traveled to Wisconsin between 6 and 7 years before examination at the WSU-VTH, but she had no other travel history since that time. Prior treatments included amoxicillin for suspected lower urinary tract infection 3 months before referral, diethylstilbesterol (dose not specified) for urinary incontinence, and methionine for urine acidification. None of these treatments changed the character of the respiratory signs.On physical examination, the dog was overweight. Temperature, pulse rate, and respiratory rate were normal, as was the dog's respiratory pattern. A cough could not be induced with tracheal palpation, and breath sounds were normal. The rest of the physical examination, except for a missing upper left 1st incisor tooth, was normal.The only abnormal result on CBC and biochemistry was mild neutrophilia (10,248/ L; reference range, 3,000-7,100/ L); a urine sample could not be obtained. On thoracic radiographs, narrowing of the trachea on the lateral view and possibly a mass in the ventral trachea at the 1st rib were observed (Fig 1). During bronchoscopy, tracheal collapse and numerous white-to-yellowish nodules were noted on the ventral and lateral walls of the trachea, typically associated with tracheal rings (Fig 2), and in the lobar bronchi. A discrete mass was not seen. The nodules were hard, did not move with pressure from the tip of the endoscope or a biopsy forceps, and appeared to be covered with mucosa. Most nodules were less than 3 mm in diameter, as gauged from the diameter of the biopsy forceps.

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Tracheobronchopathia Osteochondroplastica in a Dog

et al. 2004

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“…1,2 The distal 2/3 of the trachea and carina are the sites most commonly affected. [3][4][5][6][7] The incidence is 3 in 1,000 at autopsy, while data from bronchoscopy surveys are more varied, ranging from 1/125-1/5,000. [1][2][3] The time of diagnosis is usually above age 50 years.…”

Section: Introductionmentioning

confidence: 99%

“…10 In one recent series, the mean age at diagnosis was 63 years (range, 25-85 years). 7 Most cases are asymptomatic. However, one may complain of cough, hemoptysis, dyspnea, or recurrent pulmonary infections.…”

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confidence: 99%

Tracheobronchopathia Osteochondroplastica in a 9‐year‐old Girl

Simsek

Özçeli̇k

Demirkazık

et al. 2005

Pediatric Pulmonology

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Summary. Tracheobroncopathia osteochondroplastica (TO) is a rare disease of adult males characterized by osteocartilagious submucosal nodules protruding into the airway lumen, causing variable degrees of airway obstruction. Here we describe a case of TO in a 9-year-old girl patient presenting with chronic cough, along with a brief review of this rare benign condition. Pediatr Pulmonol. 2006; 41:95-97. ß 2005 Wiley-Liss, Inc.

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Tracheobronchopathia osteochondroplastica

et al. 2015

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Tracheobronchopathia osteochondroplastica (TBOC) is a rare disease of the trachea and bronchi characterized by submucosal nodules of osseous and cartilaginous tissue. In this series, we present three cases highlighting the varied clinical presentations of this rare disease process, which ranged from a rough voice to a chronic cough to lobar pneumonia. The disorder may mimic other lesions. We review the clinical presentations, pathophysiology, lab tests, imaging, diagnosis, and management of TBOC patients. Laryngoscope, 126:2006-2009, 2016.

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Tracheobronchopathia Osteochondroplastica

Cited by 128 publications

References 70 publications

Tracheobronchopathia Osteochondroplastica in a Dog

Tracheobronchopathia Osteochondroplastica in a Dog

Tracheobronchopathia Osteochondroplastica in a 9‐year‐old Girl

Tracheobronchopathia osteochondroplastica

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