Tracheobronchial Aspergillosis following Primary Cutaneous Aspergillosis in a Lung-Transplant Recipient

Abstract

Invasive aspergillosis, a major problem during the post-transplant period, typically presents with pneumonia or tracheobronchitis in lung transplant recipients. In contrast, primary cutaneous aspergillosis is very rarely observed in lung-transplant recipients. In this report, we describe a case of tracheobronchial aspergillosis following primary cutaneous aspergillosis in a lung-transplant recipient. Early diagnosis of tracheobronchial aspergillosis is important because occult tracheobronchial aspergillosis can be potentially lethal. Our report suggests that surveillance bronchoscopy may facilitate identification of occult tracheobronchial invasion in lung-transplant recipients with primary cutaneous aspergillosis.

Soft Tissue Abscess Caused by Aspergillus Fumigatus in an Immunosuppressive Patient

“…Brinca et al presented a case report of cutaneous aspergillosis in 2011, in this study they found a pulmonary primary focus of infection (13). Cho et al were also presented a case report of tracheobronchial aspergillosis following primary cutaneous aspergillosis in a lung-transplant recipient (22). Special attention to pulmonary symptoms and/or signs may determine whether an evaluation for pulmonary aspergillosis is needed.…”

Primary cutaneous aspergillosis presenting as a cystic lesion in the foot

“…8 Another case report of tracheobronchial aspergillosis following primary cutaneous aspergillosis in a lungtransplant recipient was reported. 9 However, we have not found any reported case of primary cutaneous aspergillosis in an immunocompetent patient after searching in PubMed and Google Scholar.…”

Invasive Tracheobronchial Aspergillosis with Bronchial Ulcers Complicated by Nontuberculous Mycobacterial Disease

“…ITBA is a rare form of invasive pulmonary aspergillosis. In previous reports, immunocompromised patients, such as those who had received organ or bone marrow transplantation, those being treated with immunosuppressive agents such as steroids and those suffering from acquired immu- (6,(10)(11)(12). The symptoms are usually non-specific, such as cough, dyspnea and respiratory failure (9,13,14).…”