Tracheobronchial amyloidosis: A surgical disease with long-term consequences

Dahl, Kevin A.; Kernstine, Kemp H.; Vannatta, Timothy L.; Karwal, Mark; Thomas, Karl W.; Schraith, Daniel F.

doi:10.1016/j.jtcvs.2004.03.036

Cited by 26 publications

(11 citation statements)

References 4 publications

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“…3) Amyloidosis, which is characterized by extracellular deposits of amyloid material, can occur with chronic inflammatory diseases (e.g., rheumatoid arthritis, Crohn's disease, and tuberculosis). 4) Spencer classified pulmonary amyloidosis into 3 categories: tracheobronchial amyloidosis (Type-1), nodular parenchymal amyloidosis (Type-2), and diffuse parenchymal (interstitial/diffuse alveolar septal) amyloidosis (Type-3). 5) According to the Spencer classification of pulmonary amyloidosis, the present case was classified as Type-2 pulmonary amyloidosis.…”

Section: Discussionmentioning

confidence: 99%

A Case of Solitary Pulmonary Nodular Amyloidosis with Sj^|^ouml;gren^|^#8217;s Syndrome

Sowa

Komatsu

Fujinaga

et al. 2013

ATCS

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Patients with Sjögren's syndrome frequently have pulmonary involvement, but the involvement of nodular pulmonary lesions, including pulmonary amyloidosis, is rare. Most cases of pulmonary amyloidosis involve multiple nodules; solitary pulmonary nodular amyloidosis, as an associated condition of Sjögren's syndrome, is very rare. In our report, we present the case of an 80-year-old female with Sjögren's syndrome who was incidentally found to have a small solitary pulmonary nodule. The nodule showed high fluorodeoxyglucose uptake and contained areas of calcification. Because the probability that the nodular lesion was malignant could not be excluded, the tumor was excised using a thoracoscopic procedure; the final diagnosis was pulmonary nodular amyloidosis. Although most cases of pulmonary amyloidosis involve multiple nodules, amyloidosis should be considered in the differential diagnosis for a solitary pulmonary nodule in patients with Sjögren's syndrome.

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Section: Discussionmentioning

confidence: 99%

A Case of Solitary Pulmonary Nodular Amyloidosis with Sj^|^ouml;gren^|^#8217;s Syndrome

Sowa

Komatsu

Fujinaga

et al. 2013

ATCS

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“…The long-term effect of this treatment on the tracheobronchial amyloidosis is entirely unknown, and the patient must continue to be monitored. (4) Lobectomy: Lobectomy had been described in the literature for treatment of pulmonary amyloidosis in severe cases with extensive airway involvement [29], even though they are rarely performed.…”

Section: Discussionmentioning

confidence: 99%

Laryngo-tracheobronchial Amyloidosis: a Case Report and Review of Literature

Wang

Yang

Chen

et al. 2014

Chinese Medical Sciences Journal

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Amyloidosis is a spectrum of diseases characterized by abnormal extracellular accumulation of proteinaceous material; its precise etiology still remains unclear. It may affect multiple organs, of which the commonest sites are larynx, bronchus and kidney. Laryngeal amyloidosis is usually a localized phenomenon rarely associated with systemic involvement, here we report a case of laryngeal amyloidosis with tracheobronchial involved. The patient was 31-years old. He had a history of open surgical operation for laryngeal amyloidosis in the left ventricle 4-years ago. This time he was suffered by amyloid deposition in his right ventricle, the lesion was excised on staged laryngoscopy under general anesthesia. After 20-months follow-up, the post-operative recovery was wonderful. The bronchoscopy examination and computerized tomography scan for chest demonstrated he also had right main bronchus amyloidosis. Being of no dyspnea, he was unwilling to accept an operation on bronchus. Though amyloidosis is a benign lesion, up to date, there are no curable treatments for such a disease, for severe cases, it may be fatal as a result of airway obstruction or respiratory failure. Here we review the pertinent references on this subject, and discuss the main managements for amyloidosis on larynx and bronchus.

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“…It affects males more than females. The median onset age is 50 -60 years old with ranging from age 27 to 85 years [4,5]. Common symptoms include dyspnea, nonproductive cough, haemoptysis and hoarseness [6].…”

Section: Discussionmentioning

confidence: 99%

Asthma-Like Tracheo-Bronchial Amyloidosis

Abdallah¹,

Smadhi²,

Mahouachi³

et al. 2012

OJRD

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Localized bronchial Amyloidosis is an uncommon disease of unknown origin. Clinical signs are not specific. Tracheobronchial symptoms are the most frequent. We report a case of a 31 year-old man complaining of asthma-like dyspnea. Bronchoscopy was performed because of ineffectiveness of antiasthmatic treatment, showed a submucosal infiltration with stenosis of both right and left upper bronchi and a complete stenosis of intermediate troncus. Multiple biopsies were performed and concluded to Amyloidosis of AL type. Oral corticosteroids were indicated with clinical improvement.

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Tracheobronchial amyloidosis: A surgical disease with long-term consequences

Cited by 26 publications

References 4 publications

A Case of Solitary Pulmonary Nodular Amyloidosis with Sj^|^ouml;gren^|^#8217;s Syndrome

A Case of Solitary Pulmonary Nodular Amyloidosis with Sj^|^ouml;gren^|^#8217;s Syndrome

Laryngo-tracheobronchial Amyloidosis: a Case Report and Review of Literature

Asthma-Like Tracheo-Bronchial Amyloidosis

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